Protein Info for CSW01_12675 in Vibrio cholerae E7946 ATCC 55056

Annotation: LPS export ABC transporter permease LptF

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 366 signal peptide" amino acids 12 to 15 (4 residues), see Phobius details amino acids 33 to 36 (4 residues), see Phobius details transmembrane" amino acids 16 to 32 (17 residues), see Phobius details amino acids 56 to 77 (22 residues), see Phobius details amino acids 101 to 121 (21 residues), see Phobius details amino acids 268 to 289 (22 residues), see Phobius details amino acids 299 to 319 (21 residues), see Phobius details amino acids 327 to 349 (23 residues), see Phobius details TIGR04407: LPS export ABC transporter permease LptF" amino acids 2 to 346 (345 residues), 398.5 bits, see alignment E=9.7e-124 PF03739: LptF_LptG" amino acids 5 to 344 (340 residues), 236.2 bits, see alignment E=2.9e-74

Best Hits

Swiss-Prot: 43% identical to LPTF_ECOLI: Lipopolysaccharide export system permease protein LptF (lptF) from Escherichia coli (strain K12)

KEGG orthology group: K07091, lipopolysaccharide export system permease protein (inferred from 100% identity to vco:VC0395_A2082)

MetaCyc: 43% identical to lipopolysaccharide ABC transporter permease (Salmonella enterica enterica serovar Typhimurium str. LT2)
RXN1R65-51 [EC: 7.5.2.5]

Predicted SEED Role

"FIG000988: Predicted permease"

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.5.2.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (366 amino acids)

>CSW01_12675 LPS export ABC transporter permease LptF (Vibrio cholerae E7946 ATCC 55056)
MIIVRYLIRETIKSQFAIFFVLFLVFLSQKFIRVLADASDGEIPTSMILSIVGLNMPAMG
LLMLPLSLYIGILLTFGRLYAESEITVMNATGIGNKFLIRAALYLALITASVAAFNALWL
APWSQDKEAHLMEQFAAENSVDLLQKGHFQRSPDGSSVVFIDNIENRKLYNVFVAQLAPR
DSILPSVMFSHSGDVKELSDGRQIITLYDGTRYEGVPTRVDYMITNFDSYDGLIGQREVK
SAERDWEALPTLSLLNNADRRAQAELQWRISLVVCIPLLTMLVVPLSAVNPRQGRFAKMG
PAILIYLTYFLALSATKSAIEDGSLPVIIGLWPINAALLLAALMVNTLDSIPVRRFKDRW
KQRKVA