Protein Info for CSW01_11900 in Vibrio cholerae E7946 ATCC 55056

Annotation: phosphopentomutase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01676: Metalloenzyme
  • amino acids 2 to 397 (396 residues), 181.6 bits, E=9.9e-58
• TIGR01696: phosphopentomutase
  • amino acids 3 to 403 (401 residues), 588 bits, E=3.5e-181

Best Hits

Swiss-Prot: 100% identical to DEOB_VIBCH: Phosphopentomutase (deoB) from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

KEGG orthology group: K01839, phosphopentomutase [EC: 5.4.2.7] (inferred from 100% identity to vcj:VCD_002000)

MetaCyc: 76% identical to phosphopentomutase (Escherichia coli K-12 substr. MG1655)
Phosphopentomutase. [EC: 5.4.2.7]; 5.4.2.7 [EC: 5.4.2.7]

Predicted SEED Role

"Phosphopentomutase (EC 5.4.2.7)" in subsystem Deoxyribose and Deoxynucleoside Catabolism (EC 5.4.2.7)

MetaCyc Pathways

• superpathway of purine deoxyribonucleosides degradation (7/7 steps found)
• purine ribonucleosides degradation (6/6 steps found)
• superpathway of pyrimidine deoxyribonucleosides degradation (6/6 steps found)
• 2-deoxy-α-D-ribose 1-phosphate degradation (3/3 steps found)

KEGG Metabolic Maps

• Pentose phosphate pathway
• Purine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 5.4.2.7

Protein Sequence (406 amino acids)

>CSW01_11900 phosphopentomutase (Vibrio cholerae E7946 ATCC 55056)
MKRAFILVLDSFGIGATADAQAFGDVGSDTLGHIADQCAQGLADNAERKGALQLPNLSKL
GLAMAHKESTGRFAPGLDERADIIGAYAHAAELSSGKDTPSGHWEIAGVPVLFEWGYFSD
KQNSFPKELTDRILARAGLDGFLGNCHASGTQVLDDLGEEHMRTGKPIFYTSADSVFQIA
CHEETFGLDRLLELCQIAREELADYNIGRVIARPFVGPGKGQFARTGNRRDLSVEPPSAT
VLQKLVEEKQGRVVSIGKIADIYAYCGITDKVKATGIPDLFEATLEQIKQAGDNTIVFTN
FVDFDSAYGHRRDVAGYAAALEYFDKRLPEVLELMQEDDILILTADHGCDPTWPGTDHTR
EHIPVLVYGKKVAPGSLGRRDTFADIGQTLASYFGTSPMDYGKNFL