Protein Info for CSW01_11860 in Vibrio cholerae E7946 ATCC 55056

Annotation: AMP-dependent synthetase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 563 PF00501: AMP-binding" amino acids 25 to 400 (376 residues), 225.2 bits, see alignment E=1.2e-70 PF23562: AMP-binding_C_3" amino acids 438 to 548 (111 residues), 28.5 bits, see alignment E=1.7e-10

Best Hits

KEGG orthology group: None (inferred from 100% identity to vch:VC2341)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (563 amino acids)

>CSW01_11860 AMP-dependent synthetase (Vibrio cholerae E7946 ATCC 55056)
MRMIQPNQFNHPPCALPPPNEMLLRWAKERPNEVYLKQIINRQFVEFTYAEVADKALRLV
SALRALGADPGDKVALISKNCAEWFICDLAMMLGDYISVPIFPTAGSETIDYCLEHSESK
ILIVGKLDDNKATAHVLAERPNLISISLPYPSAAKCQYEFQTLIKQHQPSEERPTHFDEK
LMSIVYTSGTSGQPKGAMLTYGAFTWSAQQLINHIGIEENDRLFSYLPLAHITERVYIFG
SSIIGGVLTAFPESLDTFIEDVKMHRPTLFISVPRLWTLFQQRIQDKLPQKKLNILLKIP
FVNSLIKRKLADGLGLDQARVLGCGSAPVSPALLEWYRSVGLNITEAWGMTESFAYSTLN
YPFRADKIGTVGNAGPGIELKIAEDEEILVRSKGLFAGYYKNDTATAESFNDDGWLHTGD
IGSLDSEGYLTIQGRKKDTFKTAKGKFVAPVPIEKKLFEYSRVEMMCLIGSGLPAPILLA
VPHNFPHFDRARYERTTQKVIARINSELESHEQIKGVLMIKDPWSIDNGILTPTLKIKRH
VLEKKYHDVGQNWPKGQLVVWEE