Protein Info for CSW01_11490 in Vibrio cholerae E7946 ATCC 55056

Annotation: di-trans,poly-cis-decaprenylcistransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 256 TIGR00055: di-trans,poly-cis-decaprenylcistransferase" amino acids 17 to 244 (228 residues), 317 bits, see alignment E=3.1e-99 PF01255: Prenyltransf" amino acids 24 to 244 (221 residues), 290.4 bits, see alignment E=4.3e-91

Best Hits

Swiss-Prot: 100% identical to UPPS_VIBCH: Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) (uppS) from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

KEGG orthology group: K00806, undecaprenyl diphosphate synthase [EC: 2.5.1.31] (inferred from 100% identity to vch:VC2256)

MetaCyc: 61% identical to ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific] (Escherichia coli K-12 substr. MG1655)
Di-trans,poly-cis-decaprenylcistransferase. [EC: 2.5.1.31]

Predicted SEED Role

"Undecaprenyl diphosphate synthase (EC 2.5.1.31)" (EC 2.5.1.31)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.5.1.31

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (256 amino acids)

>CSW01_11490 di-trans,poly-cis-decaprenylcistransferase (Vibrio cholerae E7946 ATCC 55056)
MFVVFLMQNLSLSQDVLPKHIAVIMDGNGRWAKAQGKPRVFGHKNGVAAVRKTISTSARL
GIKAVTLFAFSSENWRRPEEEVGVLMELFMTVLSTEIKKLHKNNLRLRVIGDKSRFSERL
QTKIAQAEQLTASNTGMVVNIAANYGGQWDILQATQALAEKVTQGELQPSDIDEDVFKQH
LTMADLPDVDLLIRTSGECRISNFMLWQLAYAEMYFTPVFWPEFDENCLIEAVTWFVNRE
RRFGCTGEQVKALMEN