Protein Info for CSW01_11400 in Vibrio cholerae E7946 ATCC 55056

Annotation: lytic transglycosylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 532 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details PF01464: SLT" amino acids 129 to 231 (103 residues), 89.8 bits, see alignment E=2.9e-29 PF01476: LysM" amino acids 349 to 391 (43 residues), 50.3 bits, see alignment 5.6e-17 amino acids 423 to 466 (44 residues), 49 bits, see alignment 1.4e-16 amino acids 481 to 523 (43 residues), 51 bits, see alignment 3.5e-17

Best Hits

KEGG orthology group: K08307, membrane-bound lytic murein transglycosylase D [EC: 3.2.1.-] (inferred from 100% identity to vco:VC0395_A1829)

Predicted SEED Role

"Membrane-bound lytic murein transglycosylase D precursor (EC 3.2.1.-)" (EC 3.2.1.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.-

Use Curated BLAST to search for 3.2.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (532 amino acids)

>CSW01_11400 lytic transglycosylase (Vibrio cholerae E7946 ATCC 55056)
MRVKFSWVLALLLVGCQSPQPVDTTTSDDQAVNPPTQSATVKKKRKPQTTATLPAGETES
VEEERVALTPQEQDDVWQRIAMQFKLGIPKDPSVDAQREWFLKNPGHLQAIASRAEPFLY
LITEKVEQRGLPLELVLLPIVESSFDPFAYSHGSAAGLWQFISSTGKRYGLKQNFWYDGR
RDVAAATDAALDYLTVLNQHFDGDWYHAIAAYNSGEGRVARAIKANKKAGKPIDFFSLDL
PKETSGYVPKLIALADVIANQEKYGISIPAIENRPVLATVDPKEQLDLAIAARYAGLTVK
ELQSFNPAYNQWATAPNGPHQLLIPVEKVERFNLAMEENRGKGIKVVRYKVKSGDTLSTI
ADKYNTTAKVIKEANQIASNQIRVGSYLFVPTSVKDEKAYALSVSNRLAKTQSVPRGQYQ
LTHTVNSGESLWTIAKQYNVPYQSLAKWNGMAPKDALRKGQKLVIWKDSKPTSGVIRTVT
YKVRSGDTLSGIANKFKVKTADIVKWNDLNSTQYLKAGQQLKLYVDVTKFSA