Protein Info for CSW01_10705 in Vibrio cholerae E7946 ATCC 55056

Annotation: flagellin E

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 378 PF00669: Flagellin_N" amino acids 5 to 141 (137 residues), 152.5 bits, see alignment E=1.1e-48 PF07196: Flagellin_IN" amino acids 195 to 245 (51 residues), 44.8 bits, see alignment 1.8e-15 PF00700: Flagellin_C" amino acids 292 to 376 (85 residues), 88.2 bits, see alignment E=5.4e-29

Best Hits

Swiss-Prot: 100% identical to FLAE_VIBCH: Flagellin E (flaE) from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

KEGG orthology group: K02406, flagellin (inferred from 100% identity to vcm:VCM66_2067)

Predicted SEED Role

"Flagellin protein FlaF" in subsystem Flagellum

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (378 amino acids)

>CSW01_10705 flagellin E (Vibrio cholerae E7946 ATCC 55056)
MAMTVNTNVSALVAQRHLNSASEMLNQSLERLSSGNRINSAKDDAAGLQISNRLETQMRG
LGIAVRNANDGISIMQTAEGAMQETTQLLQRMRDLSLQSANGSNSAAERVALQEEMAALN
DELNRIAETTSFAGRKLLNGQFMKASFQIGASSGEAVQLSLRNMRSDSLEMGGFSYVAAA
LADKQWQVTKGKQQLNISYVNAQGENENIQIQAKEGDDIEELATYINGKTDKVSASVNEK
GQLQLYIAGKETSGTLSFSGSLANELQMNLLGYEAVDNLDISSAGGAQRAVSVIDTALKY
VDGHRSELGAMQNRFQHAISNLDNVHENLAASNSRIKDADYAKETTQMIKQQILQQVSTS
VLAQAKRQPKFVLFLLRN