Protein Info for CSW01_10645 in Vibrio cholerae E7946 ATCC 55056

Annotation: flagellar motor switch protein FliG

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 348 TIGR00207: flagellar motor switch protein FliG" amino acids 17 to 346 (330 residues), 313.2 bits, see alignment E=1.2e-97 PF14842: FliG_N" amino acids 21 to 121 (101 residues), 96.6 bits, see alignment E=2.6e-31 PF14841: FliG_M" amino acids 131 to 203 (73 residues), 84.2 bits, see alignment E=1.2e-27 PF01706: FliG_C" amino acids 234 to 340 (107 residues), 144.4 bits, see alignment E=3e-46

Best Hits

Swiss-Prot: 100% identical to FLIG_VIBCH: Flagellar motor switch protein FliG (fliG) from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

KEGG orthology group: K02410, flagellar motor switch protein FliG (inferred from 100% identity to vcj:VCD_002239)

Predicted SEED Role

"Flagellar motor switch protein FliG" in subsystem Bacterial Chemotaxis or Flagellum

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (348 amino acids)

>CSW01_10645 flagellar motor switch protein FliG (Vibrio cholerae E7946 ATCC 55056)
MAKDNKDGGEVVESTIDISEIPGEEKAAILLLSLNEEDAAGIIRHLEPKQVQRVGSAMAR
AKDLSQTKVSAVHRAFLEDIQKYTNIGMGSEDFLRNALVAALGADKANNLVDQILLGTGS
KGLDSLKWMDPRQVASIIINEHPQIQTIVLSYLEPDQSAEILAQFAQRDALDLLMRIANL
EEVQPSALAELNEIMEKQFAGQAGAQAAKIGGLKAAADIMNYLDNNIESVLMEGMREKDE
DLATQIQDLMFVFENLVEVDDQGIQKLLRDVPQDVLQKALKGADDTLREKIFKNMSKRAA
EMMKDDLEAMPPIKVSDVEAAQKEILSIARRMADNGEIMLGGGADEFL