Protein Info for CSW01_10450 in Vibrio cholerae E7946 ATCC 55056

Annotation: succinate dehydrogenase cytochrome b556 subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 130 transmembrane" amino acids 20 to 51 (32 residues), see Phobius details amino acids 70 to 89 (20 residues), see Phobius details amino acids 108 to 129 (22 residues), see Phobius details PF01127: Sdh_cyt" amino acids 8 to 124 (117 residues), 102.3 bits, see alignment E=1e-33 TIGR02970: succinate dehydrogenase, cytochrome b556 subunit" amino acids 9 to 127 (119 residues), 132.1 bits, see alignment E=6.1e-43

Best Hits

Swiss-Prot: 75% identical to DHSC_ECO57: Succinate dehydrogenase cytochrome b556 subunit (sdhC) from Escherichia coli O157:H7

KEGG orthology group: K00241, succinate dehydrogenase cytochrome b-556 subunit (inferred from 100% identity to vcj:VCD_002276)

MetaCyc: 75% identical to succinate:quinone oxidoreductase, membrane protein SdhC (Escherichia coli K-12 substr. MG1655)

Predicted SEED Role

"Succinate dehydrogenase cytochrome b-556 subunit" in subsystem Succinate dehydrogenase

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (130 amino acids)

>CSW01_10450 succinate dehydrogenase cytochrome b556 subunit (Vibrio cholerae E7946 ATCC 55056)
MSKPVKERKSRPVNLDLQTISFPISAIASILHRVSGVITFVAVGILLWLLSLSLSSPVGF
MEASNIVDSFFVKFVLWGILTALAYHIAGGIRHLLMDLGHFEELESGAASAKVAFAATVV
LSLLAGVLVW