Protein Info for CSW01_10290 in Vibrio cholerae E7946 ATCC 55056

Annotation: cytochrome c biogenesis ATP-binding export protein CcmA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR01189: heme ABC exporter, ATP-binding protein CcmA
  • amino acids 2 to 203 (202 residues), 263.2 bits, E=7.1e-83
• PF00005: ABC_tran
  • amino acids 18 to 158 (141 residues), 105.8 bits, E=1.4e-34

Best Hits

Swiss-Prot: 100% identical to CCMA_VIBCH: Cytochrome c biogenesis ATP-binding export protein CcmA (ccmA) from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

KEGG orthology group: K02193, heme exporter protein A [EC: 3.6.3.41] (inferred from 100% identity to vco:VC0395_A1645)

MetaCyc: 58% identical to cytochrome c maturation protein A (Escherichia coli K-12 substr. MG1655)
RXN-21408

Predicted SEED Role

"ABC transporter involved in cytochrome c biogenesis, ATPase component CcmA" in subsystem Biogenesis of c-type cytochromes

MetaCyc Pathways

• cytochrome c biogenesis (system I type) (6/11 steps found)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.6.3.41

Protein Sequence (207 amino acids)

>CSW01_10290 cytochrome c biogenesis ATP-binding export protein CcmA (Vibrio cholerae E7946 ATCC 55056)
MLEVKNLTAIRDERILFESLSFEIHAGELVQIEGRNGTGKTTLLRIIAGLGECECGEILW
QRSKIQSDRESYHQDLLFLGHQTGIKRELTALENLRFYLAVHQQTVDDPAIFEALAKVGL
AGREDVPVAQLSAGQQRRVALARLWLSKKPLWILDEPLTAIDKQGVSVLEALFLSHAQQG
GIVILTTHQDMFADNPKLRKIRLGDPK