Protein Info for CSW01_10265 in Vibrio cholerae E7946 ATCC 55056

Annotation: c-type cytochrome biogenesis protein CcmF

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 651 transmembrane" amino acids 6 to 28 (23 residues), see Phobius details amino acids 41 to 62 (22 residues), see Phobius details amino acids 94 to 113 (20 residues), see Phobius details amino acids 125 to 144 (20 residues), see Phobius details amino acids 177 to 198 (22 residues), see Phobius details amino acids 211 to 230 (20 residues), see Phobius details amino acids 250 to 266 (17 residues), see Phobius details amino acids 276 to 299 (24 residues), see Phobius details amino acids 312 to 332 (21 residues), see Phobius details amino acids 352 to 374 (23 residues), see Phobius details amino acids 391 to 413 (23 residues), see Phobius details amino acids 426 to 445 (20 residues), see Phobius details amino acids 451 to 470 (20 residues), see Phobius details amino acids 492 to 512 (21 residues), see Phobius details amino acids 617 to 636 (20 residues), see Phobius details TIGR00353: cytochrome c-type biogenesis protein CcmF" amino acids 53 to 642 (590 residues), 863.9 bits, see alignment E=3.5e-264 PF01578: Cytochrom_C_asm" amino acids 89 to 296 (208 residues), 191.6 bits, see alignment E=1.5e-60 PF16327: CcmF_C" amino acids 316 to 639 (324 residues), 428.7 bits, see alignment E=1.5e-132

Best Hits

KEGG orthology group: K02198, cytochrome c-type biogenesis protein CcmF (inferred from 100% identity to vch:VC2052)

Predicted SEED Role

"Cytochrome c heme lyase subunit CcmF" in subsystem Biogenesis of c-type cytochromes or Copper homeostasis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (651 amino acids)

>CSW01_10265 c-type cytochrome biogenesis protein CcmF (Vibrio cholerae E7946 ATCC 55056)
MIAEIGHFALIVSLSLAILLSVLPLVGASRNNTLLMNTARPLAWGMFFLLSISFAVLLWA
FYINDFTVQYVASNSNSELPWYYRLTAVWGAHEGSLLLWVLIQAAWTVAVASFSRGMPQE
SVARVLAVMGMITVGFLLFIILTSNPFLRTLPYFPIDGRDLNPLLQDPGLIIHPPMLYMG
YVGFSVAFSFAIASLMTGRLDTAWARWSRPWTTAAWLFLTLGIVLGSWWAYYELGWGGWW
FWDPVENASFMPWLAGTALMHSLAVTEKRGTFKAWTVLLAISAFSLSLLGTFLVRSGILV
SVHAFASDPARGMFILGFLIAVIGGSLLLFAIKGASVRVRGNFELVSRENSLLVNNVLLM
TALAVVLIGTLLPLVHKQLGLGSVSIGAPFFNMLFAWLMIPFAFFMGIGPLIRWKRDQIS
TLFKPMLITAMASLVLAALMMWLNAPTFSPMAYLGWVMAWWILLLHAYELHTRATHRHRF
IVGVKKLQRSHWAMMLGHVGLAVSIIGIAMVQNYSIERDVRLAPGDNFQLNEYNFYFQGV
RDKDGPNYDGYIADFEITSQGQYVNTLHAEKRFYRTAKSMMTEAAIDRGITRDLYIAMGE
RLDDNRSWAVRIYYKPYVRWIWAGGLLMAIGGALAISDKRYRFRKNAHQEA