Protein Info for CSW01_10250 in Vibrio cholerae E7946 ATCC 55056

Annotation: c-type cytochrome biogenesis protein CcmI

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 404 transmembrane" amino acids 6 to 24 (19 residues), see Phobius details amino acids 90 to 110 (21 residues), see Phobius details TIGR03142: cytochrome c-type biogenesis protein CcmI" amino acids 3 to 117 (115 residues), 105.2 bits, see alignment E=1.3e-34 PF23914: TPR_CcmH_CycH" amino acids 119 to 274 (156 residues), 205.1 bits, see alignment E=1.2e-64 PF14559: TPR_19" amino acids 177 to 244 (68 residues), 25 bits, see alignment E=3.9e-09 PF23892: Ig_CycH" amino acids 298 to 399 (102 residues), 74.2 bits, see alignment E=1.4e-24

Best Hits

KEGG orthology group: None (inferred from 100% identity to vcj:VCD_002317)

Predicted SEED Role

"Cytochrome c heme lyase subunit CcmH" in subsystem Biogenesis of c-type cytochromes or Copper homeostasis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (404 amino acids)

>CSW01_10250 c-type cytochrome biogenesis protein CcmI (Vibrio cholerae E7946 ATCC 55056)
MWMFWISTLLLVAIAVVFVIIPFIQKRANNDQALRDELNKAFYKDRLKELEEETEEGIVA
DQQDLIADLKQTLLDDIPTQQKHQQENRVSLWMVALPSVLLVVGLSYALYAKFGHYQHVQ
AWQQVSAQLPELSKKLMSPQAELSDEEMNDLTLALRTRLHYQPDDVTGWLLLGRIGLANR
DLETAIGAMKKAFALDNEDPDVKFGYAQALMLSNDPVDQQEAKSILLKLAQRGYADLRVY
SLLAFDAFESGDFPAAIKYWSLMQQAIGPDDARYEMLSRSIESARKRMGEGMAEGQSVKV
TINLGEQVKVDPNAVLIVSIHAPGSPMPVAAARYPLGEFPRTVVLDDNNSMMEGSKLSSL
ESYVVRVRIDSDGNVATKSGDWYAESPTMKTGEPVDVVLDKQYE