Protein Info for CSW01_09765 in Vibrio cholerae E7946 ATCC 55056

Annotation: NupC/NupG family nucleoside CNT transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 405 transmembrane" amino acids 6 to 22 (17 residues), see Phobius details amino acids 33 to 52 (20 residues), see Phobius details amino acids 87 to 112 (26 residues), see Phobius details amino acids 167 to 188 (22 residues), see Phobius details amino acids 193 to 214 (22 residues), see Phobius details amino acids 252 to 277 (26 residues), see Phobius details amino acids 281 to 304 (24 residues), see Phobius details amino acids 314 to 332 (19 residues), see Phobius details amino acids 344 to 370 (27 residues), see Phobius details amino acids 381 to 403 (23 residues), see Phobius details TIGR00804: nucleoside transporter, NupC family" amino acids 5 to 401 (397 residues), 459 bits, see alignment E=7.8e-142 PF01773: Nucleos_tra2_N" amino acids 9 to 82 (74 residues), 88.7 bits, see alignment E=4.3e-29 PF07670: Gate" amino acids 93 to 189 (97 residues), 64.1 bits, see alignment E=2.2e-21 PF07662: Nucleos_tra2_C" amino acids 195 to 400 (206 residues), 262.3 bits, see alignment E=5.1e-82

Best Hits

Swiss-Prot: 55% identical to Y519_HAEIN: Uncharacterized transporter HI_0519 (HI_0519) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: K03317, concentrative nucleoside transporter, CNT family (inferred from 100% identity to vch:VC1953)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (405 amino acids)

>CSW01_09765 NupC/NupG family nucleoside CNT transporter (Vibrio cholerae E7946 ATCC 55056)
MGGVMSSLLGMGAILLVAWLFSTNRKNINLRTVSLALLLQIFFALLVLYVPAGKEALNRV
TGAVSQLINYGQDGIGFVFGGLANGSVGFVFAINVLGIIIFFSALISGLYHLGIMPKVIN
LIGGGLQKLLGTGRAESLSATANIFVGMIEAPLVVKPYLHKMTDSQFFAVMTGGLASVAG
GTLVGYASLGVELNYLIAAAFMSAPAGLLMAKIMLPETEHVDAAIAQDELDLPKSTNVVE
AIADGAMSGVKIAVAVGATLLAFVSVIALLNGLLGWFGGWFGIELSFELIMGYVFAPVAW
LIGIPWHEAITAGSLIGNKVVVNEFVAFIQLIEVKEQLSAHSQAIVTFALCGFANISTMA
ILIGGLGSLVPERRSFISQYGFRAIGAGVLANLMSASIAGVILSL