Protein Info for CSW01_09760 in Vibrio cholerae E7946 ATCC 55056

Annotation: chitinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 846 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF17957: Big_7" amino acids 85 to 151 (67 residues), 59.7 bits, see alignment E=3.7e-20 amino acids 179 to 246 (68 residues), 64.6 bits, see alignment E=1.1e-21 amino acids 336 to 404 (69 residues), 61.6 bits, see alignment E=9.3e-21 amino acids 428 to 494 (67 residues), 54.3 bits, see alignment E=1.7e-18 PF00704: Glyco_hydro_18" amino acids 523 to 725 (203 residues), 38.5 bits, see alignment E=1.1e-13

Best Hits

KEGG orthology group: K01183, chitinase [EC: 3.2.1.14] (inferred from 100% identity to vcm:VCM66_1876)

MetaCyc: 100% identical to endochitinase (Vibrio cholerae 569B)
Chitinase. [EC: 3.2.1.14]

Predicted SEED Role

"Chitinase (EC 3.2.1.14)" in subsystem Chitin and N-acetylglucosamine utilization (EC 3.2.1.14)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.14

Use Curated BLAST to search for 3.2.1.14

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (846 amino acids)

>CSW01_09760 chitinase (Vibrio cholerae E7946 ATCC 55056)
MKRYCLAAVITASLGVSYSAQAYNCAGVPVWDSSTVYVGSDKVQKTNTAYQARYWTQGND
PVTHSGQWDAWQILGQCDGGANNPPQVSIQSPLNNAKIPQGSVVGLQANASDSDGSITQV
EFLVGTQRIAIDQQAPYQVDWTATLGATSVTAIATDNQGATTSSTVNISVTPTGNPVPPT
VTLTSPTGSEQLTVGDVLAVAANATDSDGTVNAVEFYVDGQLVVIDSSEPYQFNWNAAVG
SHTFKAKAIDNDNLSTLSQEVTLTVGSGSNAGCAGLPVYSVGTAYSAGQLVQNKNQKYRC
DIAGWCSSSSGWAYEPGVGSYWKEAWSGLGACSTPPVVTLTNPTANQVILAGSTVSVAAQ
ASDADGSVMQVEFFAGNNSLGVVTQAPYAVNWLATTTGNQTLKAVATDNDSNTSESAVSV
TVSDQDLVVSLTSPTSGQTVGLGKPVNIAADATSLTNNVAKVEFVVNGAVVATDTTEPFA
YSWTPSAIGNYTVAAKATDAAGTSVTSSAAAISVVEQAQKKHRLIGYWHNFVNGAGCPIR
LADMSQAWDVIDIAFAENDRNSTGTVHFNLYAGDIYSSCPALDPAQFKQDMKALQAKGKV
FVLSLGGAEGTITLNTDQDEANFVSSLTALIKEWGFDGLDVDLESGSNLVHGSQIQARLG
RALKQIEKNIGGDMFLTMAPEHPYVQGGMVAYSGIWGAYIPVINEVRDTLDILHVQLYNN
GGLPNPYTPSAAPEGSVDMMVAQSKMLIEGFTLANGTRFEPLRDDQVAIGLPSGPSSANS
GQAPTQNILDALDCLTKGTRCGTIKPAFAYPNYAGVMTWSINWDKHDGFNFSKPVGDKLS
QMNNAQ