Protein Info for CSW01_09590 in Vibrio cholerae E7946 ATCC 55056

Annotation: competence protein ComEA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 103 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details TIGR00426: competence protein ComEA helix-hairpin-helix repeat region" amino acids 41 to 103 (63 residues), 89.2 bits, see alignment E=7.2e-30 PF12836: HHH_3" amino acids 41 to 101 (61 residues), 76 bits, see alignment E=4.1e-25 PF03934: T2SSK" amino acids 42 to 92 (51 residues), 41.4 bits, see alignment E=3.1e-14 PF00633: HHH" amino acids 43 to 70 (28 residues), 26.4 bits, see alignment E=8.7e-10

Best Hits

KEGG orthology group: K02237, competence protein ComEA (inferred from 100% identity to vcm:VCM66_1841)

Predicted SEED Role

"Competence protein ComEA"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (103 amino acids)

>CSW01_09590 competence protein ComEA (Vibrio cholerae E7946 ATCC 55056)
MQIKTKIVTLFLSLCLPTLPLLANAEETAPAAQVEEGIVITVNINTASAEELATLLKGIG
LKKAQAIVDYREANGPFTHIDDLTNVKGIGEATVRNNAARILL