Protein Info for CSW01_09565 in Vibrio cholerae E7946 ATCC 55056

Annotation: lipopolysaccharide assembly protein LapB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 389 signal peptide" amino acids 1 to 17 (17 residues), see Phobius details PF13176: TPR_7" amino acids 71 to 96 (26 residues), 20.4 bits, see alignment (E = 2.9e-07) PF13181: TPR_8" amino acids 180 to 212 (33 residues), 12 bits, see alignment 0.00015 PF13432: TPR_16" amino acids 198 to 243 (46 residues), 17.5 bits, see alignment 3.3e-06 PF14559: TPR_19" amino acids 198 to 244 (47 residues), 26.6 bits, see alignment 4.2e-09 PF18073: Zn_ribbon_LapB" amino acids 355 to 382 (28 residues), 46 bits, see alignment (E = 2.3e-15)

Best Hits

Swiss-Prot: 53% identical to LAPB_ECO57: Lipopolysaccharide assembly protein B (lapB) from Escherichia coli O157:H7

KEGG orthology group: None (inferred from 100% identity to vcj:VCD_002450)

Predicted SEED Role

"Heat shock (predicted periplasmic) protein YciM, precursor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (389 amino acids)

>CSW01_09565 lipopolysaccharide assembly protein LapB (Vibrio cholerae E7946 ATCC 55056)
MLEILFLLLPIAAAYGWYMGHRSAQQDKQKQSHQISRQYVTGLNLLLSDQSDKAVDHFIE
LLQVDNETIDTHLALGNLFRSRGEVDRAIRIHQNLISRSGLTIDQKNLALQQLAKDYMVS
GFLDRAEKIFEQLIDEPEHRESALQQLTAIYQQTREWHKAIECATALVKLGRKRMKVNIA
HFYCELAMLEKADSNDNKAIQLFKKALQEDPKCVRATISLGKLYLQNEDYQKTIDHLEMV
LEQDIDFIGEVLNTLAECYHHLGREQDLITFLRRCIANKAGVSAELMLAQLVAQHEGIAA
AQEILTRQLVKNPTMKGFYRLIDYHIAEAEEGRAKASLSTLQRLVGEQLKVKPHYRCRKC
GFSTHSLYWHCPSCKNWGSIKPIRGLDGE