Protein Info for CSW01_09525 in Vibrio cholerae E7946 ATCC 55056

Annotation: DNA translocase FtsK

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 960 transmembrane" amino acids 33 to 52 (20 residues), see Phobius details amino acids 83 to 105 (23 residues), see Phobius details amino acids 117 to 139 (23 residues), see Phobius details amino acids 146 to 166 (21 residues), see Phobius details amino acids 173 to 193 (21 residues), see Phobius details PF13491: FtsK_4TM" amino acids 28 to 199 (172 residues), 143.5 bits, see alignment E=1.1e-45 PF17854: FtsK_alpha" amino acids 467 to 567 (101 residues), 104.3 bits, see alignment E=7.3e-34 PF01580: FtsK_SpoIIIE" amino acids 575 to 788 (214 residues), 272.4 bits, see alignment E=5.4e-85 PF09397: FtsK_gamma" amino acids 894 to 954 (61 residues), 87.5 bits, see alignment 7.5e-29

Best Hits

Swiss-Prot: 100% identical to FTSK_VIBCH: DNA translocase FtsK (ftsK) from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

KEGG orthology group: K03466, DNA segregation ATPase FtsK/SpoIIIE, S-DNA-T family (inferred from 100% identity to vco:VC0395_A1493)

Predicted SEED Role

"Cell division protein FtsK" in subsystem Bacterial Cell Division or Bacterial Cytoskeleton or Bacterial RNA-metabolizing Zn-dependent hydrolases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (960 amino acids)

>CSW01_09525 DNA translocase FtsK (Vibrio cholerae E7946 ATCC 55056)
MFKENKNKVETIIKTSEEAPSSRLNGSQRLKESGLILAFLFSIFLAVALFSFNPADPSWS
QTAWGTDIHNAGGLVGAWLADTLFFVFGSLAYPLPFITAFAAWVLLRKRDEGDEIDFTLW
GTRLLGLTIVLLTSCGLADINFDDIWYFSSGGVIGDVLTSLALPTLNILGTTLVLLFLWG
AGITLLTGISWLRIVEWIGERSIAAFVGLFNRLRGEKAERVKPALVKPELPVEELEPTFS
ASMDTEIDEPAPSLRRFNIHMPEERDVPDIHFEPQVEPKVELKPEPPRQREPAPHFSRVA
AQNTQVEPVSSARTQQWDATIEELEQQARLVDDYAVEDDAVPSVLTSSTLSDVEDSILTT
AISVDEEEESLSENFNHSFNIEVEDEEVEPSIANLHWSDDEDELEETPSVMVSPAIESDW
EDEDEPDDRDVAAFQNIVSQAQANAAAQQNPFLVQKAVNLPKPTEPMPTLELLYHPEKRE
NFIDREALEEIARLVESKLADYKIQAQVVDIFPGPVITRFELDLAPGVKVSRISSLSMDL
ARSLSAMAVRVVEVIPGKPYVGLELPNMSRQTVYLSDVIASPQFKESKSPTTVVLGQDIA
GDAVVADLSKMPHVLVAGTTGSGKSVGVNVMILSMLYKASPEDVRFIMIDPKMLELSVYE
GIPHLLAEVVTDMKDASNALRWCVGEMERRYKLMSVLGVRNIKGFNDKLRMAAEAGHPIY
DPLWKDGDSMESEPPLLEKLPYIVVVVDEFADLMMVVGKKVEELIARLAQKARAAGIHLI
LATQRPSVDVITGLIKANIPTRVAFTVSTKTDSRTILDQSGAESLLGMGDMLYLPAGSSH
TIRVHGAFASDDDVHAVVNNWKARGKPNYISEIIQGDHGPEALLPGEQSESDEELDPLFD
QVVEHVVETRRGSVSGVQRRFKIGYNRAARIVEQLEAQGIVSAPGHNGNRDVLAPAPIRD