Protein Info for CSW01_09170 in Vibrio cholerae E7946 ATCC 55056

Annotation: histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 736 transmembrane" amino acids 13 to 35 (23 residues), see Phobius details amino acids 90 to 108 (19 residues), see Phobius details amino acids 280 to 300 (21 residues), see Phobius details PF00512: HisKA" amino acids 356 to 421 (66 residues), 70.4 bits, see alignment E=1.6e-23 PF02518: HATPase_c" amino acids 468 to 582 (115 residues), 102.8 bits, see alignment E=2.2e-33 PF00072: Response_reg" amino acids 604 to 716 (113 residues), 80.7 bits, see alignment E=1.4e-26

Best Hits

KEGG orthology group: None (inferred from 100% identity to vco:VC0395_A1424)

Predicted SEED Role

"Sensor histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (736 amino acids)

>CSW01_09170 histidine kinase (Vibrio cholerae E7946 ATCC 55056)
MVMAIRSSLKKKSILALTIYLAFFLAIVGTLSYWGLEVPFRKELKNNLALRAELLATQIR
EPLNNSIGVLQSLTSIGKSAADKEEQERMLRSLFSVVGGVIISGGLWPEPNLSATDPSLR
YDSLFFNKATDGQVDQLSSWNNPKAGGYDRESWYLAAEREAEGLYFWSPVYVDPYTRVEM
ITVSTPYYRNGQFAGVATVDLSLESLIQFVAATAEQYNLGVNLKDAFGVEVVSHNFRTYD
NALVSYYSFGEFNWQIEVVNANQHVDEIIFDLIINIEKGLMPILLLCVMVGYFLISHYWI
RPIVLIAKKVSESREGEIIDIRYKSQDEIRHLIDTFNQKTIYLEAEKVKAQASTKAKSAF
LATLSHEIRTPMNGVLGTAQILLKDELTSKQRQHLTSLYESGEHMMSLLNEILDYSKIEQ
GKFELDHSAFPLKSIIGSIKSIYSSLCVEKGLKFQLNSEITDGRWYYGDKARLRQIIFNL
LSNAVKFTEAGFVAIGLSEESCDEENYLIIKVQDTGIGIAQESLGRIFRPFEQAESHTTR
RFGGTGLGLAIVKQIAELMNGTVLVQSEVGQGSCFKVRVKLAITEPVTEDVKPTKAKTYP
GLRVLIVEDNRTNIMILEAFMRNKGFECHSVMDGVQAITALQESSFDLVLMDNHMPLKDG
IQATREIRQLPLPQAKILLFGCTADVFKDTRDKMLSAGADDIIAKPIAEHELDMALEQHS
ERLYQFHREPSLPSVE