Protein Info for CSW01_09130 in Vibrio cholerae E7946 ATCC 55056

Annotation: PTS fructose transporter subunit IIC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 467 transmembrane" amino acids 26 to 49 (24 residues), see Phobius details amino acids 68 to 89 (22 residues), see Phobius details amino acids 109 to 128 (20 residues), see Phobius details amino acids 140 to 162 (23 residues), see Phobius details amino acids 175 to 198 (24 residues), see Phobius details amino acids 221 to 244 (24 residues), see Phobius details amino acids 256 to 276 (21 residues), see Phobius details amino acids 282 to 308 (27 residues), see Phobius details amino acids 320 to 341 (22 residues), see Phobius details TIGR01427: PTS system, Fru family, IIC component" amino acids 12 to 342 (331 residues), 255.6 bits, see alignment E=8.4e-80 TIGR00829: PTS system, Fru family, IIB component" amino acids 375 to 459 (85 residues), 108.2 bits, see alignment E=2e-35 PF02302: PTS_IIB" amino acids 375 to 466 (92 residues), 69.3 bits, see alignment E=1.9e-23

Best Hits

KEGG orthology group: K11202, PTS system, fructose-specific IIB-like component [EC: 2.7.1.69] K11203, PTS system, fructose-specific IIC-like component (inferred from 100% identity to vch:VC1821)

Predicted SEED Role

"PTS system, fructose-specific IIBC component (EC 2.7.1.69)" (EC 2.7.1.69)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.1.69

Use Curated BLAST to search for 2.7.1.69

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (467 amino acids)

>CSW01_09130 PTS fructose transporter subunit IIC (Vibrio cholerae E7946 ATCC 55056)
MSTLTAQATNNSSNFKKLLSTMKGHLLFGTSHMLPFIVAGGVLLALAVMASGKGAVPADG
LLADISNIGIKGLVLFPIILGGFIGYSIADKPALAPAMISSGIMADMGGGFLGCIVAGFI
AGGVVFQLKKIPLSANMTALGAYFIYPLIGTLISAGIVLWGIGEPIKLFMASMNEFLASM
AGASKVVLGAILGGMTAFDMGGPINKVATLFAQTQVDTQPWLMGGVGIAICTPPLGMALA
TFLFKKKFTKQEQEAGKAAAIMGSIGISEGAIPFAANDPMRVLPSIVAGGIVGCVFGFLT
NVLLHAPWGGLITAPVSSNIPMYVVGIALGSLTTALIVGFWKPVAEEEVEDEIAEAAPTQ
AQAAPAAGEGEYDIVAVTCCPSGVAHTFMAAKALEKAGAAAGSKIKVETQGQNGIKNRIT
DLDVANAKLVILAHDIQVKDAHRFANAKVIECSTKEAMKKAAELIQA