Protein Info for CSW01_08685 in Vibrio cholerae E7946 ATCC 55056

Annotation: glycogen synthase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 484 PF08323: Glyco_transf_5" amino acids 5 to 236 (232 residues), 232.8 bits, see alignment E=7.3e-73 TIGR02095: glycogen/starch synthase, ADP-glucose type" amino acids 5 to 479 (475 residues), 520.5 bits, see alignment E=1.9e-160 PF00534: Glycos_transf_1" amino acids 297 to 443 (147 residues), 53.7 bits, see alignment E=2.9e-18 PF13692: Glyco_trans_1_4" amino acids 300 to 414 (115 residues), 42.9 bits, see alignment E=9.5e-15

Best Hits

Swiss-Prot: 100% identical to GLGA_VIBCH: Glycogen synthase (glgA) from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

KEGG orthology group: K00703, starch synthase [EC: 2.4.1.21] (inferred from 100% identity to vcm:VCM66_1666)

Predicted SEED Role

"Glycogen synthase, ADP-glucose transglucosylase (EC 2.4.1.21)" in subsystem Glycogen metabolism (EC 2.4.1.21)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.4.1.21

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (484 amino acids)

>CSW01_08685 glycogen synthase (Vibrio cholerae E7946 ATCC 55056)
MEQFNVWFTVSEVQGLVKSGGLADVAKALPQALKALHQQVAIALPAYRSVPGKEDAELVL
ETELTHWPHTQYRVLKRDLDGVPIYLIDCPAYFDRPALYAENNQAYADNGERFGFFSAAC
LDVLPKLGIQPDIIHANDWHTGLVPFLLKTRYRYDSFFEQVKSVLTVHNAIFKGIFSYHQ
LEVIPELNLSGMEFLQYGHDHVSMLRAGIAFADKVNAVSPNYAAELLTPLGAHGLVDDFV
RRARDLHGIVNGCDYSEWNPRTDHYLPATYSDEPESMRKGKALCKTALQEELHLPVTDVP
LFGMVCRLTHQKGFHYLLPILEQFLRNNVQVVIVGTGEPEVAARLNKIAHYHRAKFAFVE
TYSERLAHWVEAGSDFFLMPSEFEACGLNQIYSMAYGTLPIVREVGGLKDTVNDYDKFPE
RATGFGYQEPTPEALLITMQRALLFYLQQPEEMLKVQQRAMQQNFSWEESAQEYMKMYRL
ARFG