Protein Info for CSW01_08605 in Vibrio cholerae E7946 ATCC 55056

Annotation: YgiQ family radical SAM protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 789 TIGR03904: uncharacterized radical SAM protein YgiQ" amino acids 24 to 636 (613 residues), 857.8 bits, see alignment E=1.8e-262 PF08497: Radical_SAM_N" amino acids 24 to 370 (347 residues), 448.9 bits, see alignment E=1.3e-138 PF04055: Radical_SAM" amino acids 371 to 576 (206 residues), 45.3 bits, see alignment E=1.7e-15 PF11842: DUF3362" amino acids 585 to 728 (144 residues), 120.3 bits, see alignment E=1.3e-38

Best Hits

Swiss-Prot: 100% identical to Y1711_VIBCH: UPF0313 protein VC_1711 (VC_1711) from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

KEGG orthology group: None (inferred from 100% identity to vcm:VCM66_1651)

Predicted SEED Role

"FIG01202089: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (789 amino acids)

>CSW01_08605 YgiQ family radical SAM protein (Vibrio cholerae E7946 ATCC 55056)
MHSEVTPIHHYKKYWAECFGTAPFLPTSREEMDQLGWDSCDVIIVTGDAYVDHPSFGMAI
IGRLLEAQGFRVGIIAQPEWQTKDAFMTLGKPNLFFGVTAGNMDSMINRYTADKKIRHDD
AYTPNNKGGMRPDRCSLVYSQRCREAYKDVPIVLGGIEASLRRVAHYDYWSDKVRRSILL
DAKADILLFGNAERALVEVAHRLANGESINKMVDIRGTAVNLAQVPEHFKIIDSTRIDQP
NKPFVPSNPYEVETQCATKGDEKEEAQPITIRPSRHDAKTTAVRLPSFEKLVNDRILYAH
ASRVLHLETNPYSGRALVQRHGDRELWVNQAPIPLTTEEMDFVFGLYYARVPHPKYGDAK
IPAYDMIKTSVNIMRGCFGGCSFCSITEHEGRIIQNRSQESIINELKEIRDKVPGFTGVI
SDLGGPTANMYRLGCSDPKAEANCRRPSCVFPGICHKLNTDHKHTIDLYRAARDVDGIKK
VVIASGVRYDLAIESPEYVRELVTHHVGGYLKIAPEHTEKGPLSMMMKPGMGTYDRFKEL
FEKYSAEAGKKQYLIPYFIAAHPGTEDEDMVNLALWLKSNNYRCDQVQNFYPSPMCNATA
MYHAEVNPLKRVKYKKPEKVPVAKGEAQRRLHKALLRYHDPANWPMIREALIAMGKRHLI
GDRPECLIPEKDSDLVTPAQSRKSGRHGANRFATKHTHSQPGFDALRGNKSGGQGRPNSG
NKSNQGKPAGSKPTGSKPTANKPAGNQSARSEQNRGQQGQRGSATGGKPQGSGRPASRGN
TQRQPQRAR