Protein Info for CSW01_08510 in Vibrio cholerae E7946 ATCC 55056

Annotation: pentaheme c-type cytochrome TorC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 394 transmembrane" amino acids 20 to 39 (20 residues), see Phobius details TIGR02162: trimethylamine-N-oxide reductase c-type cytochrome TorC" amino acids 7 to 394 (388 residues), 682.8 bits, see alignment E=8.2e-210 PF03264: Cytochrom_NNT" amino acids 16 to 187 (172 residues), 254 bits, see alignment E=2e-79 PF22113: Mtrc-MtrF_II-IV_dom" amino acids 49 to 204 (156 residues), 32.9 bits, see alignment E=1.4e-11

Best Hits

KEGG orthology group: K03532, trimethylamine-N-oxide reductase (cytochrome c) 1, cytochrome c-type subunit TorC (inferred from 100% identity to vcj:VCD_002685)

Predicted SEED Role

"Cytochrome c-type protein NapC" in subsystem Nitrate and nitrite ammonification or trimethylamine N-oxide (TMAO) reductase

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (394 amino acids)

>CSW01_08510 pentaheme c-type cytochrome TorC (Vibrio cholerae E7946 ATCC 55056)
MKSLILKMWHTMTRPAVHISLGVLTLGGFIAGVIFWGGFNTALEATNTEEFCISCHTMRD
NVYQELQTTVHWKNHSGVRATCPDCHVPHEWTAKIARKMQASKEVFAQIFGDLDTPEKFE
ERRIELAKHEWDRFAANKSLECKNCHNYESMDFDQMSATARIQMKQAAERDQSCIDCHKG
IAHNLPKNMESSSGLIGELEGMASNTKYSNGETLVSVRFLPVYEDDQAKVEAGLLNPASE
VKVLTEKGDMMQVEINGWRKSKGFGRVIQEDFGMNIAVASLLKEAAMSDAIVTTGEQKVD
DMTGLPWEQVSAKVWMKKEAMLNDINPVWEKAREAYKTNCSVCHTQPDEAHFDANTWPGM
FDGMLAFVNFDTDSEALVLKYLQKHSSDFAEGHH