Protein Info for CSW01_08455 in Vibrio cholerae E7946 ATCC 55056

Annotation: peptide ABC transporter permease SapC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 295 transmembrane" amino acids 28 to 50 (23 residues), see Phobius details amino acids 95 to 121 (27 residues), see Phobius details amino acids 133 to 154 (22 residues), see Phobius details amino acids 159 to 180 (22 residues), see Phobius details amino acids 211 to 238 (28 residues), see Phobius details amino acids 258 to 282 (25 residues), see Phobius details PF12911: OppC_N" amino acids 14 to 65 (52 residues), 55.2 bits, see alignment 5.3e-19 PF00528: BPD_transp_1" amino acids 112 to 294 (183 residues), 91.9 bits, see alignment E=4.5e-30

Best Hits

Swiss-Prot: 57% identical to SAPC_SALTY: Peptide transport system permease protein SapC (sapC) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K02034, peptide/nickel transport system permease protein (inferred from 100% identity to vco:VC0395_A1287)

MetaCyc: 55% identical to putrescine ABC exporter membrane protein SapC (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-328 [EC: 7.6.2.16]

Predicted SEED Role

"Peptide transport system permease protein SapC"

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.6.2.16

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (295 amino acids)

>CSW01_08455 peptide ABC transporter permease SapC (Vibrio cholerae E7946 ATCC 55056)
MLSDSIYQEEHIPTQFERFWRSFRANNLAMFGLWSLLFIALVTILSPWIAPYDPQMHSSV
LLLPPSWEPEGTVDYFLGTDDLGRDILSRLIDGSLFSIGAAVLITLIATLVGGTIGALAG
MTKGLLSSTLNHILDTVMSIPSLLLAIIFVAFLGAGEFNILLAIGLALIPRFIRSVYVAV
HNEVEKDYVMAARLDGANEFYLLWHSIFPNILPIIVAEITMALSIAILDITALGFLGLGA
QSPSTEWGAMLGDSVELIYIAPWTVTLPGLAIMFTVVVINLVGDGARQALNAGVE