Protein Info for CSW01_08290 in Vibrio cholerae E7946 ATCC 55056

Annotation: serine protease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 548 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details transmembrane" amino acids 524 to 542 (19 residues), see Phobius details PF00089: Trypsin" amino acids 33 to 268 (236 residues), 174.3 bits, see alignment E=3.3e-55 PF13365: Trypsin_2" amino acids 62 to 232 (171 residues), 29.3 bits, see alignment E=1.4e-10 TIGR03501: GlyGly-CTERM domain" amino acids 524 to 545 (22 residues), 17 bits, see alignment (E = 4e-07)

Best Hits

KEGG orthology group: None (inferred from 100% identity to vco:VC0395_A1254)

Predicted SEED Role

"trypsin, putative"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (548 amino acids)

>CSW01_08290 serine protease (Vibrio cholerae E7946 ATCC 55056)
MNKTFLSGVVGTLLFTSFQFSASGTESGVSSRIIGGEQATAGEWPYMVALTARNSSHVFC
GGSYLGGRYVLTAAHCVDKEDPAKGDVLLGAFDMNDVNTAERIHVRQIYVHNSYITASMG
NDIAVLELERDPLPRRSVQISDSSDFNELTKDSPMTVIGFGNRKEVDGEKSDPATILHQV
QVPFVPLPECKTKGSDQDAKNNYSQLTNNAFCAGSFGKDACSGDSGGPIFFDSNNGRKQM
GVVSWGDGCGRANSPGVYTNLSVFNDWLDDQQLGLSYRQKRDLGVVRPGSYTHNLTFTNN
GNADINLGNTFVFVVGISRTDAAAIVNNSCTGVLASGASCDVEFSYNITEHKQSYVKLII
GSSTYKTGAVHAYLYFDALDAAPSETVSFLANLPVHNTHVNDHPWTVVGNGLQTSALPAG
EESVILLENLPQGRLKFHYKLSSSEVLDQLFVYVNDKFKGKYFNNTENLATLDMYGTNNK
VRFVYRRHSGSTDDQSRAILSQISYDPKFFDLPPPLDIRIGDSGGGSLGGAALALLFGCG
WLRRRQRV