Protein Info for CSW01_08185 in Vibrio cholerae E7946 ATCC 55056

Annotation: hydroxyneurosporene synthase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 372 transmembrane" amino acids 12 to 28 (17 residues), see Phobius details PF07143: CrtC" amino acids 76 to 246 (171 residues), 152.7 bits, see alignment E=1.6e-48 PF17186: Lipocalin_9" amino acids 250 to 372 (123 residues), 96.5 bits, see alignment E=1.5e-31

Best Hits

KEGG orthology group: None (inferred from 100% identity to vcm:VCM66_1567)

Predicted SEED Role

"AttH component of AttEFGH ABC transport system"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (372 amino acids)

>CSW01_08185 hydroxyneurosporene synthase (Vibrio cholerae E7946 ATCC 55056)
MRRFRLRLKPWVWLSLGALFFMVGFIGYEQDEYHSMLLHSADPEHSTVQAVFEPVLPNHP
VRLPTDFASRPEFEQEWWRLYALLEDEQGNPLSVQWNFLRLAQDERDTLGWQTPQLYFSS
IVINGKKVSLRDQKIARGGIGQAGMGDQPFRMWIDNWTWRSLGMGPLPGNLHLSTDHFAL
NLQLRALGPYVLSGDRGYQVKQELLSLASYQFQLPYIAVHGDLVVSPELPALRVRGHAWL
SKEWGSELVANDLEGTDSFVIPLNDKQWLTVNRFRHRGVPDSVYGMLHNLNGKSVALLNR
DIQLEALSSSSLSNGKRVPLRWRLAIPKYQVNVSIEPLDRDAWQTFLIPYWEGRIKVLGS
HNQTGFMQLSGY