Protein Info for CSW01_08085 in Vibrio cholerae E7946 ATCC 55056

Annotation: ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 387 transmembrane" amino acids 21 to 42 (22 residues), see Phobius details amino acids 189 to 215 (27 residues), see Phobius details amino acids 236 to 255 (20 residues), see Phobius details amino acids 267 to 290 (24 residues), see Phobius details amino acids 297 to 318 (22 residues), see Phobius details amino acids 358 to 375 (18 residues), see Phobius details PF12698: ABC2_membrane_3" amino acids 21 to 366 (346 residues), 181.7 bits, see alignment E=1.1e-57

Best Hits

KEGG orthology group: K09686, antibiotic transport system permease protein (inferred from 100% identity to vcm:VCM66_1548)

Predicted SEED Role

"ABC-type multidrug transport system, permease component"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (387 amino acids)

>CSW01_08085 ABC transporter permease (Vibrio cholerae E7946 ATCC 55056)
MVELKMKHAIPRQWTLLRHDKWLFSCLTWVPILLAVSIWWIFSQGIARDLPFGVVDFSHS
QLSRQLIREVDATSTLLVSQHFASVDEASQAMRSNQIYGFMVIPAQFDKAIYRQEQPQVT
TFYNSQMILVGKLVNSAVVQAQGTFNAQVDVMKNLATKTHTTLAAMGRSVPVRTQITPLF
NQNTNYAQFLVSAIVPALWQITIVVSTILILAANYRHYGLKSWLAQSPLTQLTRTLLPYL
PIFMLQGLGFLIWFYDVLRWPMFGHFSTLLLAQSITVVACVIMGAFFYFLTLDPARAMSF
AGAFTAPSFAFMGITFPASDMNTLAQAWRNLLPISHYIEVQVNQVSYGLEALSSLQPMVN
MWGYLLPLGLALLLIRKHLAREMGAAV