Protein Info for CSW01_08010 in Vibrio cholerae E7946 ATCC 55056

Annotation: MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 477 signal peptide" amino acids 1 to 32 (32 residues), see Phobius details transmembrane" amino acids 48 to 69 (22 residues), see Phobius details amino acids 79 to 101 (23 residues), see Phobius details amino acids 107 to 127 (21 residues), see Phobius details amino acids 139 to 160 (22 residues), see Phobius details amino acids 166 to 184 (19 residues), see Phobius details amino acids 196 to 217 (22 residues), see Phobius details amino acids 223 to 247 (25 residues), see Phobius details amino acids 267 to 292 (26 residues), see Phobius details amino acids 303 to 321 (19 residues), see Phobius details amino acids 333 to 353 (21 residues), see Phobius details amino acids 359 to 381 (23 residues), see Phobius details amino acids 402 to 420 (19 residues), see Phobius details amino acids 440 to 462 (23 residues), see Phobius details PF07690: MFS_1" amino acids 19 to 409 (391 residues), 180.5 bits, see alignment E=9.4e-57 PF06779: MFS_4" amino acids 22 to 161 (140 residues), 28.8 bits, see alignment E=1.6e-10 PF06609: TRI12" amino acids 32 to 415 (384 residues), 33 bits, see alignment E=5e-12 PF00083: Sugar_tr" amino acids 47 to 175 (129 residues), 54 bits, see alignment E=2.8e-18

Best Hits

KEGG orthology group: None (inferred from 100% identity to vcm:VCM66_1537)

Predicted SEED Role

"putative multidrug-efflux transporter"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (477 amino acids)

>CSW01_08010 MFS transporter (Vibrio cholerae E7946 ATCC 55056)
MSQPVDRKTFLGIFFTVFLPMFLAAVDQTLLATATPAIVRDLGNLQLSSWIAIGYMLASA
ASVPVYGWLGDQYGRKPMLMIALSIFALGSVICAFAMNMPWLVAGRIVQGLGSGGLMSLS
QALIGELVPPRERARFQGYFSSLFAVASIGGPVLGGVLVTYLSWQWLFWFNLPLVGIALY
RLARFQFVQSSRKSEASIDVAGLILFPSMMTLIIYWLSAGGHYFPWFSVTSISLVSAFVL
TSLLFIAQQKRVTASFLPLRLLARREIHIPLLSTFIFAACLFALIFFLPIFLQLGLRVNA
AQSGLLLIPLSCGIIGGAYTTGKVIAKTGVPKFLPVFGMSLSSCAFAVLAMFSLSAPVVS
AIAALCGLGLGTVMPSTQVLVQTLAGKANLGRITAMASLSRSLGASVGTAFFGTLIYSLL
PGLSPNSGLQAIAALPQSEILHAFQIGFAVAALLALLGALNALRAPKIQLDDYAFDS