Protein Info for CSW01_07940 in Vibrio cholerae E7946 ATCC 55056

Annotation: DUF2309 domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 862 PF10070: DabA" amino acids 46 to 831 (786 residues), 883.2 bits, see alignment E=9.1e-270

Best Hits

Swiss-Prot: 100% identical to Y1522_VIBCM: UPF0753 protein VCM66_1522 (VCM66_1522) from Vibrio cholerae serotype O1 (strain M66-2)

KEGG orthology group: K09822, hypothetical protein (inferred from 100% identity to vch:VC1582)

Predicted SEED Role

"Hypothetical transmembrane protein coupled to NADH-ubiquinone oxidoreductase chain 5 homolog" in subsystem CO2 uptake, carboxysome or Respiratory Complex I

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (862 amino acids)

>CSW01_07940 DUF2309 domain-containing protein (Vibrio cholerae E7946 ATCC 55056)
MARAINSAYRSFINSSATDDRRTRMNAPRSLSALSTTANPALSTLVEQVCALIAPNWPLD
RMIAVSPYWKRIDKPFAQAAAELKQLAASPMTMTLSDYHLRWQNKQIQSADLQQAIAEQN
SDLSESTLIAALQQPTAPSHPWPLLCDTVDSRRDLEHHPAWNDAITHQISQFCAAYFDHH
QADWSPDQQTGLFATWREAMIHDRSITLLLNETSVKQKATKLPEDAMAAIEQTLAQLAIA
PAQQETYLQAVLMRISGWASWCAYLAWQAGFEGRHDEHLRDLLAIRLCWENLLDDGERGM
GSVWLQWQQSWAPRQSCEEDRALRIALLWQRSAEIAYQRQLFAALTSAQESAPQSSYPEV
QAAFCIDVRSEVIRRHLEAQSPHIQTLGFAGFFGLPIRYQLLGTEASRPQLPGLLAPSLI
VSDSTGNEDQDAKLALRRRARLKRHFSWRAFHHLPASTFTLVETTGLAYLTKLLKRTLSY
PALSASVERFAFTEHEWQSVKPQFTRDPQTLAQRAQMAANILRALGIATEQARLVLLVGH
GSQTQNNPQRAGLDCGACCGQSGEVNARTLAALLNDQAVRQALPEYGISLRDDVHFIAAL
HNTTTEAMRLFDRHEIPTSHREALEQLDQQLTAASHGARQERAPSLELNHNHQAPPSKDN
ALSAQQLEQAFLRRAHDWAQTRPEWGLTNNAAFIIAPRQRSKQAKLDGRVFLHEYQPERD
PEGQLLTQIMTAPMLVTHWINMQYFASTVDNRRFGSGNKTLHNVVGGNIGLFEGNGGDLR
CGLALQSLHDGQGWRHEALRLTVVIDAPRERIEQVMASHRVVEHLVKHEWLYLARFADQG
IEIYLQGTWQRITQPSSDSSAR