Protein Info for CSW01_07935 in Vibrio cholerae E7946 ATCC 55056

Annotation: NADH-quinone oxidoreductase subunit L

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 516 transmembrane" amino acids 6 to 24 (19 residues), see Phobius details amino acids 32 to 52 (21 residues), see Phobius details amino acids 63 to 82 (20 residues), see Phobius details amino acids 94 to 111 (18 residues), see Phobius details amino acids 117 to 136 (20 residues), see Phobius details amino acids 153 to 175 (23 residues), see Phobius details amino acids 190 to 209 (20 residues), see Phobius details amino acids 228 to 248 (21 residues), see Phobius details amino acids 258 to 278 (21 residues), see Phobius details amino acids 287 to 325 (39 residues), see Phobius details amino acids 349 to 370 (22 residues), see Phobius details amino acids 377 to 396 (20 residues), see Phobius details amino acids 408 to 429 (22 residues), see Phobius details amino acids 440 to 462 (23 residues), see Phobius details PF00361: Proton_antipo_M" amino acids 113 to 333 (221 residues), 139.3 bits, see alignment E=1.6e-44

Best Hits

KEGG orthology group: K05577, NADH dehydrogenase I subunit 5 [EC: 1.6.5.3] (inferred from 100% identity to vcm:VCM66_1521)

Predicted SEED Role

"NADH dehydrogenase, subunit 5" in subsystem Respiratory Complex I

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.6.5.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (516 amino acids)

>CSW01_07935 NADH-quinone oxidoreductase subunit L (Vibrio cholerae E7946 ATCC 55056)
MSELSPQWLLVSLYLGGLVLSLWLPQQQWRIAKFATLAGFIAMLGNTLFAIGQASINLVP
VDGLGIVMAILVSLLGWVITRFAHRYLQGEAQQARFVTATLFTLSCVALLVTSQHLLVIV
LAWSGTSVGLHRLLTFYPERKAARVVAHKKFLVSRFAEICLLLALGLIYLDVGSLSLQEI
HFALNAQDSLPLSLTGAALLLAFAAILKTAQLPLHGWLIQVMEAPTPVSALLHAGVVNMG
GFVLLRVAELIGLVPSAQWLLVIVGSLTAVLAGMVMLTRISIKVRLAWSTCAQMGFMLME
IGLGLYELALLHLVAHSLYKAYAFLSSGEAVERARLHDFQAPQSVNGKAVGALLAVGLSA
ALILILHHLWQSLTSNLHLPNAVVAILALGFAPLLWQSGRFTPSGLSLGVLRVALLTQLY
FVWHLLFAGLAPELRPASPLALSFVMFCFITLYLMQVLLCLYPKSRLSLWLYPWVYHGFY
LDETFTRLTFKYWPVQLTLPTALSSTQAQPTTGERV