Protein Info for CSW01_07695 in Vibrio cholerae E7946 ATCC 55056

Annotation: N-acetylglucosamine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00480: ROK
  • amino acids 2 to 300 (299 residues), 250.2 bits, E=3.3e-78
• PF02685: Glucokinase
  • amino acids 6 to 240 (235 residues), 27.1 bits, E=2.2e-10

Best Hits

Swiss-Prot: 100% identical to NAGK_VIBCH: N-acetyl-D-glucosamine kinase (nagK) from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

KEGG orthology group: K00884, N-acetylglucosamine kinase [EC: 2.7.1.59] (inferred from 100% identity to vco:VC0395_A1138)

MetaCyc: 53% identical to N-acetyl-D-glucosamine kinase (Escherichia coli K-12 substr. MG1655)
N-acetylglucosamine kinase. [EC: 2.7.1.59]

Predicted SEED Role

"N-acetyl-D-glucosamine kinase (EC 2.7.1.59)" (EC 2.7.1.59)

MetaCyc Pathways

• N-acetylglucosamine degradation II (3/3 steps found)
• chitin derivatives degradation (6/8 steps found)

KEGG Metabolic Maps

• Aminosugars metabolism
• Nucleotide sugars metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.1.59

Protein Sequence (302 amino acids)

>CSW01_07695 N-acetylglucosamine kinase (Vibrio cholerae E7946 ATCC 55056)
MYYGFDVGGTKIEFGAFNEQLERVATERVATPTDDYAKLVETIAGLVHKYDAQFGVEGTV
GLGIPGMEDADNGCVLTVNVPAAKGKPLRADLETKLGRAVKVENDANCFALSEAWDDELK
EAASVMGLILGTGFGGGLVYEGKVFSGRNHVAGEIGHMRLPIDAWFHLGEKAPLLGCGCG
NKGCMDNYLSGRGFELLYEHYYGEKKKAIDIITAQKEGESKAVEHVERFMELLAICFANI
FTANDPHVVVLGGGLSNYDLIYEEMPKRVPKHLLSVAKCPKIVKAKHGDSGGVRGAAFLN
IK