Protein Info for CSW01_07650 in Vibrio cholerae E7946 ATCC 55056

Annotation: ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 232 transmembrane" amino acids 24 to 52 (29 residues), see Phobius details amino acids 61 to 83 (23 residues), see Phobius details amino acids 102 to 122 (21 residues), see Phobius details amino acids 143 to 167 (25 residues), see Phobius details amino acids 200 to 221 (22 residues), see Phobius details PF00528: BPD_transp_1" amino acids 44 to 217 (174 residues), 36.9 bits, see alignment E=1.6e-13

Best Hits

Swiss-Prot: 38% identical to ANTRP_HALVD: Probable anion ABC transporter permease protein HVO_1887 (HVO_1887) from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2)

KEGG orthology group: K05773, putative tungstate transport system permease protein (inferred from 100% identity to vcj:VCD_002851)

Predicted SEED Role

"ABC-type tungstate transport system, permease protein" in subsystem ABC transporter tungstate (TC 3.A.1.6.2)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (232 amino acids)

>CSW01_07650 ABC transporter permease (Vibrio cholerae E7946 ATCC 55056)
MSLWQTTLDALHLLVSLDPKLWEIVAVSFSVSLTAIALVLIPSVVLSFVLAYTNFRGKWT
LLSLINTLQAVPTVVIGLLLYMLLSRAGPLGDWQMLFTQQAMILGQALICFPILVAMMHG
ALQSTDRRSLETSMTLGASVPRLFATLVWEARFPLMAATIAGFSRIVTEVGCSMMVGGNI
MGLTRNIPTAISLESNKGAFAQGVALGMVLLALALGLNFLLSSLRGKGYLRT