Protein Info for CSW01_07530 in Vibrio cholerae E7946 ATCC 55056

Annotation: ABC transporter ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 610 transmembrane" amino acids 36 to 57 (22 residues), see Phobius details amino acids 87 to 108 (22 residues), see Phobius details amino acids 172 to 190 (19 residues), see Phobius details amino acids 196 to 213 (18 residues), see Phobius details amino acids 282 to 303 (22 residues), see Phobius details amino acids 310 to 336 (27 residues), see Phobius details PF00664: ABC_membrane" amino acids 40 to 324 (285 residues), 108.4 bits, see alignment E=5.5e-35 PF00005: ABC_tran" amino acids 388 to 536 (149 residues), 110 bits, see alignment E=1.4e-35

Best Hits

KEGG orthology group: K06148, ATP-binding cassette, subfamily C, bacterial (inferred from 100% identity to vch:VC1499)

Predicted SEED Role

"ABC-type multidrug transport system, ATPase and permease component"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (610 amino acids)

>CSW01_07530 ABC transporter ATP-binding protein (Vibrio cholerae E7946 ATCC 55056)
MRITKIGCILINMTYFNDTISRSWLITQVKKHRAKLLFANFIAVVATLISVPIPLLMPLM
VDEVLLNHPAKGVEVMNQFLPQGWQTATGYIMLTLLMVVVMRIASQLLNILQSRQFTLVS
KTITYEMRRKMIEKLGRISIRQYETRGSGGINAHLITDIETIDQFIGSTLSKFLISLLTV
IGTAIVLLWLEWRLGLFILLVNPIVIYFSRMLGSQVKHLKKRENQAFERFQNRLVETLDG
IYQLRAANKEREFLNRLISDADAVRENADKYAWQSEAAGRLSFLLFLLGFELFRAVAMLM
VVFSDLTIGQIFAVFGYLWFMLSPVQELLGIQFSWYAAKAALKRINSLLELEEEYRPISK
VNPFTQLGEVDIEINNIHFSYDGESQVLNDLSLHIPAGKKVALVGASGGGKSTLIQLLIG
VYRAQSGAIRFNGQHCDDISFDVIRDQIAVVLQQPILFNDTLRHNLTLGGQFSDDVLWQA
LDIAQLQDVITKLDQGLESQIGRNGIRLSGGQRQRLAIARMVLSNPKFVILDEATSALDT
ATEAALHLALSKFLHGRTTLIVAHRLSAVKQADLIYVLEDGHVSQSGTHHELLEQEGLYQ
TLYGSVQSQH