Protein Info for CSW01_07230 in Vibrio cholerae E7946 ATCC 55056

Annotation: cytochrome-c oxidase, cbb3-type subunit I

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 477 transmembrane" amino acids 21 to 45 (25 residues), see Phobius details amino acids 65 to 85 (21 residues), see Phobius details amino acids 97 to 120 (24 residues), see Phobius details amino acids 133 to 154 (22 residues), see Phobius details amino acids 164 to 186 (23 residues), see Phobius details amino acids 208 to 229 (22 residues), see Phobius details amino acids 239 to 258 (20 residues), see Phobius details amino acids 278 to 298 (21 residues), see Phobius details amino acids 310 to 329 (20 residues), see Phobius details amino acids 350 to 370 (21 residues), see Phobius details amino acids 387 to 407 (21 residues), see Phobius details amino acids 437 to 459 (23 residues), see Phobius details TIGR00780: cytochrome c oxidase, cbb3-type, subunit I" amino acids 11 to 468 (458 residues), 757.2 bits, see alignment E=3.7e-232 PF00115: COX1" amino acids 17 to 447 (431 residues), 398.5 bits, see alignment E=1.9e-123

Best Hits

Swiss-Prot: 78% identical to CCON1_PSEST: Cbb3-type cytochrome c oxidase subunit CcoN1 (ccoN1) from Pseudomonas stutzeri

KEGG orthology group: K00404, cb-type cytochrome c oxidase subunit I [EC: 1.9.3.1] (inferred from 100% identity to vco:VC0395_A1053)

MetaCyc: 80% identical to cbb3-1 cytochrome c oxidase subunit N (Pseudomonas putida KT2440)
CYTOCHROME-C-OXIDASE-RXN [EC: 7.1.1.9]

Predicted SEED Role

"Cytochrome c oxidase subunit CcoN (EC 1.9.3.1)" in subsystem Terminal cytochrome C oxidases (EC 1.9.3.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.9.3.1

Use Curated BLAST to search for 1.9.3.1 or 7.1.1.9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (477 amino acids)

>CSW01_07230 cytochrome-c oxidase, cbb3-type subunit I (Vibrio cholerae E7946 ATCC 55056)
MQMSQEKQLEQNYNYTVVRQFTLVTILWGIVGMAVGVLIAAQLVWPQLNFDTPWLTYSRL
RPLHTNAVIFAFGTSALFATSYYVVQRTCQTRLFGGPLVPFTFWGWQAIIVSAAITLPLG
YTSGKEYAELEWPIDIAIAAVWVAYAVVFFGTLVKRKTSHIYVANWFFGAFIITVAVLHI
VNSMALPVSMGKSYSIYAGAVDAMVQWWYGHNAVGFLLTAGFLGMMYYFVPKQAERPVYS
YRLSIVHFWALISLYIWAGPHHLHYTALPDWTQSLGMVMSLVLFAPSWGGMINGIMTLSG
AWHKLRYDPILRFLIVSLSFYGMSTFEGPMMSIKTVNALSHYTDWTIGHVHSGALGWVAM
VSIGSVYHLIPRLFGQERMYSVSLINAHFWLATIGTVLYIVAMWISGVMQGLMWRAVNSD
GTLTYSFVESVQASYPFYTVRFIGGFIFLSGMFLMAYNAYKTISAPKNSLKAIVQPA