Protein Info for CSW01_07215 in Vibrio cholerae E7946 ATCC 55056

Annotation: cytochrome-c oxidase, cbb3-type subunit III

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 326 transmembrane" amino acids 6 to 28 (23 residues), see Phobius details amino acids 57 to 78 (22 residues), see Phobius details PF14715: FixP_N" amino acids 38 to 83 (46 residues), 83.6 bits, see alignment 9.5e-28 TIGR00782: cytochrome c oxidase, cbb3-type, subunit III" amino acids 113 to 323 (211 residues), 195.4 bits, see alignment E=6.2e-62 PF13442: Cytochrome_CBB3" amino acids 156 to 229 (74 residues), 51.4 bits, see alignment E=1.7e-17 amino acids 244 to 317 (74 residues), 41.3 bits, see alignment E=2.3e-14 PF00034: Cytochrom_C" amino acids 160 to 222 (63 residues), 31.7 bits, see alignment E=4.8e-11 amino acids 243 to 320 (78 residues), 27.3 bits, see alignment E=1.1e-09

Best Hits

KEGG orthology group: K00406, cb-type cytochrome c oxidase subunit III [EC: 1.9.3.1] (inferred from 100% identity to vcj:VCD_002907)

Predicted SEED Role

"Cytochrome c oxidase subunit CcoP (EC 1.9.3.1)" in subsystem Terminal cytochrome C oxidases (EC 1.9.3.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.9.3.1

Use Curated BLAST to search for 1.9.3.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (326 amino acids)

>CSW01_07215 cytochrome-c oxidase, cbb3-type subunit III (Vibrio cholerae E7946 ATCC 55056)
MTTFWSLWIIVITVGTLLGCAILLVWCLKDKMGVEEGVDMGHEYDGIRELNNPLPKWWTY
LFIGTFIFAAIYLTLYPGLGSFKGILGWQSSDQTVRSLEESRASIAAAQQNKQLVQYSKE
LDDAEAYYGEAFKRLAYQDGTTNLREIPDIAADSDALKVGQRLFLQNCSQCHGSDARGQK
GFPNLTDDAWLYGGEPQAIVTTIRHGRIGQMPAWKDILGEQGVKEVVSYTLSLSGRSVNA
KEAEAGKARFAVCSACHGTDGKGNPAFGAPNLTDNDWLFGDSRAEVTETVMNGRSGVMPA
WINTLGEEKIQLVAAYVWSLSNSENK