Protein Info for CSW01_07155 in Vibrio cholerae E7946 ATCC 55056

Annotation: spermidine/putrescine ABC transporter permease PotB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 286 transmembrane" amino acids 12 to 35 (24 residues), see Phobius details amino acids 69 to 91 (23 residues), see Phobius details amino acids 101 to 120 (20 residues), see Phobius details amino acids 148 to 172 (25 residues), see Phobius details amino acids 199 to 226 (28 residues), see Phobius details amino acids 252 to 273 (22 residues), see Phobius details PF00528: BPD_transp_1" amino acids 84 to 283 (200 residues), 60.2 bits, see alignment E=1.2e-20

Best Hits

Swiss-Prot: 69% identical to POTB_SALTY: Spermidine/putrescine transport system permease protein PotB (potB) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K11071, spermidine/putrescine transport system permease protein (inferred from 99% identity to vcm:VCM66_1383)

MetaCyc: 70% identical to spermidine preferential ABC transporter membrane subunit PotB (Escherichia coli K-12 substr. MG1655)
ABC-25-RXN [EC: 7.6.2.11, 7.6.2.16]; 7.6.2.11 [EC: 7.6.2.11, 7.6.2.16]

Predicted SEED Role

"Spermidine Putrescine ABC transporter permease component PotB (TC 3.A.1.11.1)" in subsystem Polyamine Metabolism (TC 3.A.1.11.1)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.6.2.11 or 7.6.2.16

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (286 amino acids)

>CSW01_07155 spermidine/putrescine ABC transporter permease PotB (Vibrio cholerae E7946 ATCC 55056)
MMSKKLNLQNAIVTLIVGWLVLFVLIPNLMIIGTSFLTRDEANLIKFAFTFENYTRLLDP
LYGKVMLHSFYMAIVATLICLVIGYPFAYIVAKMPEKWRPFMLFLIIVPFWTNSLIRTYG
LKIVLGTQGILNQALMSLGLIDAPLRIMFTETAVMIGLVYILLPFMILPLYSAIEKLDGT
YIEAARDLGANKFQTLVRVILPLTMPGIIGGCLLVLLPALGMFYIADLLGGAKNLLIGNV
IKSQVLNARDWPFGAATSIALTLAMAIMLYAYYRAGKLLNKKVELD