Protein Info for CSW01_06960 in Vibrio cholerae E7946 ATCC 55056

Annotation: molecular chaperone

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 PF00012: HSP70" amino acids 130 to 259 (130 residues), 41.4 bits, see alignment E=5.8e-15

Best Hits

Swiss-Prot: 55% identical to YEGD_ECOLI: Uncharacterized chaperone protein YegD (yegD) from Escherichia coli (strain K12)

KEGG orthology group: K04046, hypothetical chaperone protein (inferred from 100% identity to vco:VC0395_A0999)

Predicted SEED Role

"Putative heat shock protein YegD" in subsystem ZZ gjo need homes

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (450 amino acids)

>CSW01_06960 molecular chaperone (Vibrio cholerae E7946 ATCC 55056)
MFIGFDYGTANCSVASMQDGRPVLIPLEGDSLYIPSTLAAPTRESVSEHLFRHRHIAPAD
ALGEQLLRRSVASNREEGIDLQFADVVFGQAALDLYLSDPHEVYYVKSPKSFLGAMGLHD
IQLSFFEDLVCAMMANIKAQAEAHSDAVIQDAVIGRPVNFHGRGGEDSNQQAENILRRAA
TRAGFRHLEFQFEPVAAGLEYEATLTEDKTVLVVDIGGGTTDCSLIQMGPSWRGKADRTQ
SLIAHTGQRVGGNDLDIHLAFKALMTPFGFGTQTQSGLDMPITQFWNPIAINDVSAQAKF
FSRENLADLKRLHKEAREPEKLARLLAVYHDTLGYSLVKKAEEAKIALSDTARAIAQIKV
LSELLEVEIQREAMIEAIDVPKTKMIELVTEAVTLGGVTPDVIFMTGGSARSPILRAGVE
QALPNVPIVSGNYFGSVTAGLARWAQVCFR