Protein Info for CSW01_06620 in Vibrio cholerae E7946 ATCC 55056

Annotation: EamA family transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 292 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details transmembrane" amino acids 39 to 57 (19 residues), see Phobius details amino acids 69 to 89 (21 residues), see Phobius details amino acids 95 to 113 (19 residues), see Phobius details amino acids 120 to 139 (20 residues), see Phobius details amino acids 146 to 164 (19 residues), see Phobius details amino acids 173 to 193 (21 residues), see Phobius details amino acids 202 to 224 (23 residues), see Phobius details amino acids 236 to 256 (21 residues), see Phobius details amino acids 262 to 283 (22 residues), see Phobius details PF00892: EamA" amino acids 146 to 276 (131 residues), 58.6 bits, see alignment E=4.3e-20

Best Hits

Swiss-Prot: 55% identical to RHTA_SALTY: Threonine/homoserine exporter RhtA (rhtA) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: None (inferred from 100% identity to vco:VC0395_A0929)

MetaCyc: 54% identical to L-threonine/L-homoserine exporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-242; TRANS-RXN0-0244

Predicted SEED Role

"Integral membrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (292 amino acids)

>CSW01_06620 EamA family transporter (Vibrio cholerae E7946 ATCC 55056)
MPTIKSPLLIAILSLLAAMITIQSGASIAKQLFPLVGPGGTVALRISLSALILMLIFRPW
RARLSWPQWRSMCIYGASLGGMQLSFYFAIERIPLGIGVALEFSGPLLLALLSSKRKKDL
IWVALAILGIVFLLPDMNGVDALDPIGVALALIAGGFWAGYIWFGQRAGSVGSGGMTVSI
GMLVAAVIYFPIATQLAEASIFSWSILPMALLVAVMSSALPYSLEMVALSRLSTQHFSVL
MSLEPAIAAMAGLAILGETLQWSQWLAIFMIITASMGSTLSAAKSPTKVTQE