Protein Info for CSW01_06480 in Vibrio cholerae E7946 ATCC 55056

Annotation: PTS sugar transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 446 transmembrane" amino acids 38 to 59 (22 residues), see Phobius details amino acids 81 to 105 (25 residues), see Phobius details amino acids 113 to 131 (19 residues), see Phobius details amino acids 139 to 162 (24 residues), see Phobius details amino acids 183 to 204 (22 residues), see Phobius details amino acids 223 to 245 (23 residues), see Phobius details amino acids 251 to 270 (20 residues), see Phobius details amino acids 290 to 310 (21 residues), see Phobius details amino acids 345 to 370 (26 residues), see Phobius details amino acids 393 to 415 (23 residues), see Phobius details TIGR00410: PTS system, lactose/cellobiose family IIC component" amino acids 19 to 428 (410 residues), 376.7 bits, see alignment E=8.1e-117 PF02378: PTS_EIIC" amino acids 35 to 354 (320 residues), 237.5 bits, see alignment E=1.1e-74

Best Hits

KEGG orthology group: K02761, PTS system, cellobiose-specific IIC component (inferred from 100% identity to vch:VC1282)

Predicted SEED Role

"PTS system, cellobiose-specific IIC component (EC 2.7.1.69)" in subsystem Beta-Glucoside Metabolism (EC 2.7.1.69)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.1.69

Use Curated BLAST to search for 2.7.1.69

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (446 amino acids)

>CSW01_06480 PTS sugar transporter (Vibrio cholerae E7946 ATCC 55056)
MNPMKLYDAIIGIVEKHIAPIAAKVGNQPHVRAMRDGFIVAMPFIIVGSFILIFAFPPFA
EDTTNVFGRVWLNFATTHFDIIMMPFNMSMGIMTIFVSLGVAYSLAKAYKMDGITSAVLS
LMSFLLVAAPAKEDSLSMAHMGGTGIFTAVMCAFFAVELYRFMKKHNITIRMPEQVPPAI
ARSFEVLLPVLAIFLTLYPLSLFVQAEYGMLIPDAVMAMFKPLISASNTLPAIIGALLVC
QLLWFAGIHGAAIVVGLLSPIFLTNISANIDAFVTGQPVPNIFTQPFWDFYIFIGGSGAT
LALVILMSFSRSAHLKSIGRMSAVPGFFQINEPVIFGSPVVMNPILFLPFVFAPVINATI
AYFAIQLGFVGMGVATTPWTTPAIIGASWGSGWTFTPVLLVVGLLILDLLIYLPFFKMFE
KQVLEQEQPVESKVKAAQPGRQGVTA