Protein Info for CSW01_06440 in Vibrio cholerae E7946 ATCC 55056

Annotation: C4-dicarboxylate ABC transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 427 transmembrane" amino acids 7 to 34 (28 residues), see Phobius details amino acids 51 to 71 (21 residues), see Phobius details amino acids 83 to 105 (23 residues), see Phobius details amino acids 110 to 128 (19 residues), see Phobius details amino acids 136 to 160 (25 residues), see Phobius details amino acids 174 to 194 (21 residues), see Phobius details amino acids 222 to 242 (21 residues), see Phobius details amino acids 248 to 270 (23 residues), see Phobius details amino acids 280 to 300 (21 residues), see Phobius details amino acids 320 to 350 (31 residues), see Phobius details amino acids 361 to 385 (25 residues), see Phobius details amino acids 403 to 425 (23 residues), see Phobius details PF06808: DctM" amino acids 9 to 423 (415 residues), 300 bits, see alignment E=1.4e-93 TIGR00786: TRAP transporter, DctM subunit" amino acids 17 to 423 (407 residues), 351.6 bits, see alignment E=2.7e-109

Best Hits

KEGG orthology group: None (inferred from 100% identity to vch:VC1275)

Predicted SEED Role

"TRAP dicarboxylate transporter, DctM subunit, unknown substrate 6"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (427 amino acids)

>CSW01_06440 C4-dicarboxylate ABC transporter (Vibrio cholerae E7946 ATCC 55056)
MIGIVMFFVALFALLLGFPVAFTFGGIALIFGLWAEGIEMFAFMPYRIQSIMENTVLMAV
PLFVFMGLVLQKTKLAEQLLESMGRLFGGIHGGVAISTVLVGTLLAASTGVVGASVVAMG
LISLPVMLKYRYDKGLACGTICASGTLGQIIPPSIVLILLGDVLGVPVGDLFQAALWPGL
MLVAAYIIYILIYAKLNPQAAMPIEPDADLSRRQEVVKALKAVIPPLALIVVVLGSIFAG
VATPTESAALGGAGAILLALAYGQFSWSMVYDASKETVKVTAMVFAILLGATAFSMAFTY
TGGDELVEEWMMNLPGDKWGFLIVTMLVILILGFFIDFVEICFIIVPILAPVAVLMDVDM
TWFAILIAMNLQTSFLTPPFGFSLFYLKGVAPKSVTTMDIYRGVVPFILIQILVLISLMV
FPSFYGM