Protein Info for CSW01_06370 in Vibrio cholerae E7946 ATCC 55056

Annotation: sugar efflux transporter SetB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 404 transmembrane" amino acids 7 to 28 (22 residues), see Phobius details amino acids 43 to 62 (20 residues), see Phobius details amino acids 74 to 92 (19 residues), see Phobius details amino acids 98 to 120 (23 residues), see Phobius details amino acids 133 to 155 (23 residues), see Phobius details amino acids 162 to 183 (22 residues), see Phobius details amino acids 211 to 231 (21 residues), see Phobius details amino acids 247 to 266 (20 residues), see Phobius details amino acids 278 to 297 (20 residues), see Phobius details amino acids 304 to 324 (21 residues), see Phobius details amino acids 336 to 357 (22 residues), see Phobius details amino acids 363 to 384 (22 residues), see Phobius details PF07690: MFS_1" amino acids 12 to 221 (210 residues), 47 bits, see alignment E=1.8e-16 amino acids 217 to 387 (171 residues), 62 bits, see alignment E=4.9e-21

Best Hits

Swiss-Prot: 31% identical to SETB_SALTY: Sugar efflux transporter B (setB) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K03291, MFS transporter, SET family, sugar efflux transporter (inferred from 100% identity to vch:VC1261)

MetaCyc: 31% identical to sugar exporter SetB (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-82

Predicted SEED Role

"Sugar efflux transporter A"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (404 amino acids)

>CSW01_06370 sugar efflux transporter SetB (Vibrio cholerae E7946 ATCC 55056)
MYRDKTALLFIMSTLVTGLCGAFFYPLSSLFIVEALDASPMQLSLYMVLAVVSSVIVSQW
LARQSDRHWQRKTILLVSLICYLITVVSFMFIRSYSLAIMVVVLFASVSGASFGQLFALG
REYADQHLTDKTTFLSTMRAGIAIAWVFGPPAAFMLKASFGFNAAFAVSALIVFLGIVLI
ARFLPAGVKTASAVGTTPVELGQYSPRKRALIVLYCVTLVCTFGSNNLYITSMPLYLSRE
LMVPEHWLGLLFGTAALCEIPVMLMAGKLAERWGTNKLLMFGITSGILFYGVMLTHTGFV
AMMAAQVLNGFFIGVCATLGMVVLQDMMQDRLGTASTLFSSMLSISTLVASLSVGVVGEF
YNYFSTLYVSLTGAFSALLLLALFSQLQRKAIPTEAVQSGVSVH