Protein Info for CSW01_06005 in Vibrio cholerae E7946 ATCC 55056

Annotation: vancomycin high temperature exclusion protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 254 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details transmembrane" amino acids 33 to 52 (20 residues), see Phobius details PF02698: DUF218" amino acids 71 to 191 (121 residues), 77.3 bits, see alignment E=5.3e-26

Best Hits

Swiss-Prot: 44% identical to SANA_HAEIN: Protein SanA homolog (sanA) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: K03748, SanA protein (inferred from 100% identity to vcm:VCM66_1141)

Predicted SEED Role

"SanA protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (254 amino acids)

>CSW01_06005 vancomycin high temperature exclusion protein (Vibrio cholerae E7946 ATCC 55056)
MGTKKPSNLTLRAVVFSALAHLRRLPWRKLSQTLLWLTIGVVAGLLAIDRWVSWQTQNNI
INDAQNTPPFQVAVVLGTSKYIGKTLNEYYTNRIDAAIALYQQGKVRNFLLSGDNAHRSY
NEPWTMKRDLLRAGIPAENISLDYAGFRTLDSIVRAKEIFDTDNFLIITQRFHCERALFI
ARYQDIQASCLAVPGPSNHSGFKVRLREVFARAYAVFDLFVLDTQPKFLGPKEPIIVESD
TESTSNDTSSNSAE