Protein Info for CSW01_06000 in Vibrio cholerae E7946 ATCC 55056

Annotation: GGDEF domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 443 transmembrane" amino acids 7 to 25 (19 residues), see Phobius details amino acids 219 to 239 (21 residues), see Phobius details TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 272 to 429 (158 residues), 148 bits, see alignment E=1e-47 PF00990: GGDEF" amino acids 274 to 426 (153 residues), 134.2 bits, see alignment E=1.9e-43

Best Hits

KEGG orthology group: None (inferred from 100% identity to vco:VC0395_A0806)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (443 amino acids)

>CSW01_06000 GGDEF domain-containing protein (Vibrio cholerae E7946 ATCC 55056)
MKVLPRVLLGLVAVTIVTVLLYWQFGSAKRVLIEPQHYAYFTTNDQTAGGTSTSALSLNG
NTAKVDCELNASRYAWPYCGISIHLNPDPQRGLDLSDIHTIRLNVDLQGPAAEPAAMRLY
LRNFNPIYSQLDDEYTHKYNGLEFVPGVGKGVIDIPIRSLQVMTWWLVDNRIAIEHSAPE
FSNVNKIEFATGSASPLGQYQLTLHQVELIGDYVAGEKLFLAMLIMWAVAGAWLSALEIR
RNRREVLRARMRQEHLQRLNHSLHEQNIKFVEMAHRDALTGAINRHGIRDWLQDQARLVR
WQLNHVSVLFIDIDYFKQVNDVYGHSLGDDLLREFALVISREIRESDKLVRWGGEEFVVF
CAQTTLEQAIELAERLRAKIADHSWIHGGAITCSIGIAQMGDERITETVSRADEALYRAK
RLGRNRIEVHYGLMAKSSDGEKG