Protein Info for CSW01_05060 in Vibrio cholerae E7946 ATCC 55056

Annotation: cation:proton antiporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 528 signal peptide" amino acids 1 to 19 (19 residues), see Phobius details transmembrane" amino acids 44 to 62 (19 residues), see Phobius details amino acids 74 to 96 (23 residues), see Phobius details amino acids 111 to 129 (19 residues), see Phobius details amino acids 140 to 162 (23 residues), see Phobius details amino acids 169 to 186 (18 residues), see Phobius details amino acids 197 to 217 (21 residues), see Phobius details amino acids 223 to 239 (17 residues), see Phobius details amino acids 246 to 265 (20 residues), see Phobius details amino acids 271 to 291 (21 residues), see Phobius details amino acids 303 to 324 (22 residues), see Phobius details amino acids 333 to 351 (19 residues), see Phobius details PF00999: Na_H_Exchanger" amino acids 8 to 347 (340 residues), 120 bits, see alignment E=1.1e-38 PF02254: TrkA_N" amino acids 388 to 504 (117 residues), 72.6 bits, see alignment E=3.6e-24

Best Hits

KEGG orthology group: None (inferred from 100% identity to vch:VC0992)

Predicted SEED Role

"putative Glutathione-regulated potassium-efflux system protein KefB" in subsystem Potassium homeostasis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (528 amino acids)

>CSW01_05060 cation:proton antiporter (Vibrio cholerae E7946 ATCC 55056)
MDLILLSAAFLAGFIALKCHLPPLVGFLIAGFALNAYGFTSNDTLSLLADLGVTLLLFTI
GLKLEVKTLLAKEIWAGSTIHNLLSTALFTLLLLIFKQLGLDSLADLSFDKLILIGFALS
FSSTVFAVKSLQEKGEMNATYGTLAIGILVMQDIFAVVFLTASTGKLPEWYAIGLFVLPL
LRPLFYELLDWVGHGEMLVLFGIFFALVVGAGSFQLVGMKPDLGALILGMMLASHHKASE
LSKALFNLKELFLVCFFLNIGLSAHPTTTGIMLALLLLLLLPIKGVLYFWVIHQFHFRVR
TSLLASLSLFNFSEFGLIVGGLAFKMGWINSDILVALAVSVPLSFILAAPIERKGHAIYQ
RSAKWLKEQAAESLHTRDRLIDPGEAQVLILGMGRIGRGAYEELTSRHGEICLGVEIREE
AANSHREEGRNVISGDATDPDFWERIFDTGKVKLVLLAMPHHQANQIALEQLQKRHYQGQ
IAAIAEYPDQIESLLEHGAHAAFNIYSEAGTGFARHVCEQLKPNFTRR