Protein Info for CSW01_05050 in Vibrio cholerae E7946 ATCC 55056

Annotation: transcription/translation regulatory transformer protein RfaH

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 165 PF02357: NusG" amino acids 2 to 96 (95 residues), 75.8 bits, see alignment E=1.6e-25 TIGR01955: transcription elongation factor/antiterminator RfaH" amino acids 4 to 163 (160 residues), 246.6 bits, see alignment E=5.2e-78

Best Hits

KEGG orthology group: K05785, transcriptional antiterminator RfaH (inferred from 100% identity to vch:VC0990)

Predicted SEED Role

"Transcriptional activator RfaH" in subsystem Transcription factors bacterial

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (165 amino acids)

>CSW01_05050 transcription/translation regulatory transformer protein RfaH (Vibrio cholerae E7946 ATCC 55056)
MKRWYLLYCKRGEQQRAKMHLENQSVECFYPEVCVEKILRGKRQMVQEPLFPSYMFVRFD
FENGPSFTTVRSTRGVVDFVRLGPHPRELQGDLIYQLKQLDCEQLKHATKQLPEKGQTVR
VARGQFAGIEAIYLEPDGDTRSIMLVKMISQQVPMSIENTDWEVT