Protein Info for CSW01_04950 in Vibrio cholerae E7946 ATCC 55056

Annotation: sulfate transporter CysZ

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 transmembrane" amino acids 27 to 47 (21 residues), see Phobius details amino acids 67 to 89 (23 residues), see Phobius details amino acids 139 to 159 (21 residues), see Phobius details amino acids 165 to 184 (20 residues), see Phobius details amino acids 205 to 237 (33 residues), see Phobius details PF07264: EI24" amino acids 11 to 227 (217 residues), 200.3 bits, see alignment E=1.8e-63

Best Hits

Swiss-Prot: 100% identical to CYSZ_VIBCH: Sulfate transporter CysZ (cysZ) from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

KEGG orthology group: K06203, CysZ protein (inferred from 100% identity to vco:VC0395_A0490)

MetaCyc: 55% identical to sulfate:H+ symporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN0-586

Predicted SEED Role

"Sulfate transporter, CysZ-type" in subsystem Cysteine Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (250 amino acids)

>CSW01_04950 sulfate transporter CysZ (Vibrio cholerae E7946 ATCC 55056)
MQISSRSGFGYFSYGIRLALTPGIRRFVVLPLLANIILVGGAMYYLFSHLDTWISEWIGQ
LPSFLSWLSYVLWPLLALTILATFSYFFSTLANFIASPFNGLLAEKVEQHLSGERIGEEG
VWALVKDVPRILSREWRKLLYVLPKALGLFLLLLIPALGQTLGPIAWFLFTAWMLAIQYC
DYPFDNHKISFHDMRNTLKQNQSKAYGFGMLVAFFTSIPIVNLFIVPVAVCGATAMWVME
FKIQHSPLRQ