Protein Info for CSW01_04910 in Vibrio cholerae E7946 ATCC 55056

Annotation: PhoH family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 367 PF02562: PhoH" amino acids 120 to 323 (204 residues), 326 bits, see alignment E=1.3e-101 PF13604: AAA_30" amino acids 125 to 276 (152 residues), 30.2 bits, see alignment E=5.6e-11

Best Hits

Swiss-Prot: 79% identical to PHOL_ECOL6: PhoH-like protein (ybeZ) from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

KEGG orthology group: K06217, phosphate starvation-inducible protein PhoH and related proteins (inferred from 100% identity to vco:VC0395_A0483)

Predicted SEED Role

"Phosphate starvation-inducible protein PhoH, predicted ATPase" in subsystem Phosphate metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (367 amino acids)

>CSW01_04910 PhoH family protein (Vibrio cholerae E7946 ATCC 55056)
MSNKIITLEINLEPSDNHRLASLCGPFDDNIKHLERRLGVEINYRGNFFTIVGQPHTAAA
ALDIIKTLYVETAPVRGQITDIEPEQIHLAIKESGVLEQHSESSIAHGKEVFVKTKKGVI
KPRTPNQAQYLMNMVTHDITFGVGPAGTGKTYLAVAAAVDALERQEIRRILLTRPAVEAG
EKLGFLPGDLSQKVDPYLRPLYDALFEMLGFERVEKLIERNVIEVAPLAYMRGRTLNDAF
IILDESQNTTVEQMKMFLTRIGFNSRAVITGDVTQIDLPRGAKSGLRHAIEVLNEVDEIS
FNFFQADDVVRHPVVARIVNAYEKWEAQDQKERKEYEQRRREERENKLLEMQRAEMTLSH
NNESNPS