Protein Info for CSW01_04905 in Vibrio cholerae E7946 ATCC 55056

Annotation: endoribonuclease YbeY

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 154 PF02130: YbeY" amino acids 22 to 142 (121 residues), 131 bits, see alignment E=1.2e-42 TIGR00043: rRNA maturation RNase YbeY" amino acids 39 to 144 (106 residues), 128.2 bits, see alignment E=7.1e-42

Best Hits

Swiss-Prot: 100% identical to YBEY_VIBCH: Endoribonuclease YbeY (ybeY) from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

KEGG orthology group: K07042, probable rRNA maturation factor (inferred from 100% identity to vch:VC0960)

Predicted SEED Role

"Metal-dependent hydrolase YbeY, involved in rRNA and/or ribosome maturation and assembly"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (154 amino acids)

>CSW01_04905 endoribonuclease YbeY (Vibrio cholerae E7946 ATCC 55056)
MSIELDLQLAVENEHGLPSEAEFALWLTRTITPFQAQAEVTVRIVDEAESHALNLNYRGK
DKPTNVLSFPFEAPSGMEMDLLGDLVICRQVVEREAIEQNKPLQAHWAHMVVHGSLHLLG
YDHIEDDEAEEMESLETEIMQEMGFTDPYLAEKE