Protein Info for CSW01_04880 in Vibrio cholerae E7946 ATCC 55056

Annotation: luciferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 204 signal peptide" amino acids 1 to 30 (30 residues), see Phobius details PF04390: LptE" amino acids 41 to 161 (121 residues), 55.4 bits, see alignment E=4.8e-19

Best Hits

Swiss-Prot: 30% identical to LPTE_HAEIN: LPS-assembly lipoprotein LptE (lptE) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: K03643, LPS-assembly lipoprotein (inferred from 100% identity to vch:VC0954)

Predicted SEED Role

"LPS-assembly lipoprotein RlpB precursor (Rare lipoprotein B)" in subsystem KDO2-Lipid A biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (204 amino acids)

>CSW01_04880 luciferase (Vibrio cholerae E7946 ATCC 55056)
MRNTLFPTLKWSLLVLMTSLLTACGFHLRGDYDIPQELSRMSLTSYDQYSTFTRMVHRQL
RLNKIDLQAPAEDLPNLHLLSESTGERTLSLYQNTRAAEIELTFVASYRVTVPELGSRTF
TTSVTRSYLDNPLTALAKSVERDMIEDEMRKLAASQIVRQMARLKADFARKTLDDESIEG
KGITDYRVDTQEVANPVSTEGSSE