Protein Info for CSW01_04855 in Vibrio cholerae E7946 ATCC 55056

Annotation: rod shape-determining protein RodA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 373 transmembrane" amino acids 21 to 41 (21 residues), see Phobius details amino acids 53 to 70 (18 residues), see Phobius details amino acids 76 to 96 (21 residues), see Phobius details amino acids 139 to 157 (19 residues), see Phobius details amino acids 163 to 181 (19 residues), see Phobius details amino acids 187 to 206 (20 residues), see Phobius details amino acids 269 to 295 (27 residues), see Phobius details amino acids 310 to 335 (26 residues), see Phobius details amino acids 341 to 362 (22 residues), see Phobius details TIGR02210: rod shape-determining protein RodA" amino acids 20 to 367 (348 residues), 458 bits, see alignment E=1.1e-141 PF01098: FTSW_RODA_SPOVE" amino acids 24 to 367 (344 residues), 393.3 bits, see alignment E=5.1e-122

Best Hits

Swiss-Prot: 66% identical to RODA_SHIFL: Peptidoglycan glycosyltransferase MrdB (mrdB) from Shigella flexneri

KEGG orthology group: K05837, rod shape determining protein RodA (inferred from 100% identity to vco:VC0395_A0472)

MetaCyc: 66% identical to peptidoglycan glycosyltransferase MrdB (Escherichia coli K-12 substr. MG1655)
Peptidoglycan glycosyltransferase. [EC: 2.4.1.129]

Predicted SEED Role

"Rod shape-determining protein RodA" in subsystem Bacterial Cytoskeleton or Peptidoglycan Biosynthesis

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.4.1.129

Use Curated BLAST to search for 2.4.1.129

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (373 amino acids)

>CSW01_04855 rod shape-determining protein RodA (Vibrio cholerae E7946 ATCC 55056)
MKMDPATGQNRALFERFHIDLPLLLGVLALMGFGLVVMYSASGQSLAMMDRQAMRMAMAL
IIMVILAQIPPRTYESAAPILFFCGVILLVCVLLFGEISKGAQRWLDLGFVRFQPSELLK
LAVPLMVARYIGKHALPPSFKTLFASLVMVFVPTILIAKQPDLGTSILIAASGIFVIFLA
GISWKLITAAAVAIGAFVPVLWFFLMHEYQKTRVRTLFDPESDPLGAGYHIIQSKIAIGS
GGLSGKGWLHGTQSQLEFLPERHTDFIFAVIAEEWGMIGILVLLSLYLFIIGRGLYLASH
AQTSFGRMMAGSIVLSFFVYVFVNIGMVSGILPVVGVPLPLISYGGTSMVTLMAGFGILM
SIHTHRKAFSKTI