Protein Info for CSW01_04190 in Vibrio cholerae E7946 ATCC 55056

Annotation: DEAD/DEAH box helicase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 950 979 PF13091: PLDc_2" amino acids 28 to 149 (122 residues), 29.9 bits, see alignment E=1.1e-10 PF04851: ResIII" amino acids 218 to 365 (148 residues), 128.9 bits, see alignment E=4.5e-41 PF00270: DEAD" amino acids 239 to 367 (129 residues), 36.9 bits, see alignment E=8e-13 PF00271: Helicase_C" amino acids 436 to 538 (103 residues), 49.2 bits, see alignment E=1.4e-16 PF00717: Peptidase_S24" amino acids 843 to 957 (115 residues), 24.7 bits, see alignment E=4e-09

Best Hits

KEGG orthology group: None (inferred from 100% identity to vcm:VCM66_0770)

Predicted SEED Role

"ATP-dependent RNA helicase YejH"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (979 amino acids)

>CSW01_04190 DEAD/DEAH box helicase (Vibrio cholerae E7946 ATCC 55056)
MMSDRQSFLYSGHKLSSGGANDPLLPRLVQAINHATEIEISVSFIQPSGLDLLFDPLFDA
VQSGAQVKLLTSDYLSITHPVALRRLMLLTERGAQCRVFECGQHSFHMKSYIFVRCEQGE
ILEGCAWIGSNNISKTALLDSHEWALRHDFEPPETSAAALEFLHIRQQFASIFNHTNSKD
LTHTWIDHYLERYQQAKKQHGMPILADSQDEQSEPPAPNAVQVEALTALNATRAQGFSRG
LVVLATGMGKTWLAAFDALQTQSTKVLFVAHREEILLQAEKTFCQLIPNAKTGLYNGVTQ
NTQAMLLFASVATIGKQNHLQRFAADHFDYIVVDEFHHAAARSYRNLLTYFKPKFLLGLT
ATPERSDQADILSLCDSNLVFERNLVHGIDEKILVPFDYHGIYDQAVNYQEIPWRNGKFD
PDSLDNALATQRRAEHVYQHWHQKKQTRTLAFCVSKKHADFMAEFCLSKGIKAIAVYSDS
KVRRNQALQWLDSGKIDILFSVDLFNEGTDLPAIDTILMLRPTESKILFLQQLGRGLRRS
IETQKSKLVVIDFIGNHDSFLNRPTTLYNVSHLKDALAKHQQQALPDGCHVTFDITLLNF
WQQLTRKMRFSVQDEYQQLAHQLAHRPTASEFFYHGIEISKVRKQAQSWFHLVASQENDP
ELAEIVTRYGDFLLHGIESTGMSKSFKAILLEALLELDGLRTPPTLATLAECSYTVIARR
PDLMAEDLTENAKQFKAADKDWLNYWRNNPIKAFTNKATKQATWFSIDSQQRFVANFDIR
EQDLERLHDCIQELVDLRLAEYAQRPKQHKENLIKAKSKAAVISLIPEQKTIGTPIPFYP
ELKIACGHFKRGSEREVQTYFVPDGYGLLDPTRHFVSPASGNSMNGGKNPIQDGDLLLLE
WVTPSSAGSISNLTMAIETQDETGDNQYLLRVVRKIAPNQYELQAQNPSYPNMPATDAMK
TFARLKAVIKNNSQQSQTR