Protein Info for CSW01_04025 in Vibrio cholerae E7946 ATCC 55056

Annotation: Fe2+-enterobactin ABC transporter substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 325 signal peptide" amino acids 1 to 29 (29 residues), see Phobius details PF01497: Peripla_BP_2" amino acids 58 to 293 (236 residues), 53.4 bits, see alignment E=1.2e-18

Best Hits

KEGG orthology group: K02016, iron complex transport system substrate-binding protein (inferred from 100% identity to vcj:VCD_003550)

Predicted SEED Role

"Ferric vibriobactin, enterobactin transport system, substrate-binding protein ViuP (TC 3.A.1.14.6)" in subsystem Iron acquisition in Vibrio (TC 3.A.1.14.6)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (325 amino acids)

>CSW01_04025 Fe2+-enterobactin ABC transporter substrate-binding protein (Vibrio cholerae E7946 ATCC 55056)
MRINITMKNIFILLSVILGCLFSGFVSAQQNVWPRTFQNADGSITTIPSQPKRILSTAVT
VTGTLLAIDAPVIASAATTQSTFFEQWRKLAELRQVKKLWPAGSVDLESVYVEQPDLIVV
SMIGADSARDQIPLLQAIAPTILVDYSDQTWQSLAQQLGLATGLEEQAERTIHNFEQWTK
QVRDVLDLPKGRANIVSYHGPGVVNAVAKAQSAHAQLLQSVGVVLEEPDPAWQAGSIVHR
DFLRIHYEHLTQLQAETTFLITMTDQQAQAFLHDPILKNLPSIQRKQVYGLGENSFRIDL
FSAREIINSLLRRFAGEQAQSLVMP